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Polyfunctional Fc-effector profiles mediated by IgG subclass selection distinguish RV144 and VAX003 vaccines.
Chung AW, Ghebremichael M, Robinson H, Brown E, Choi I, Lane S, Dugast AS, Schoen MK, Rolland M, Suscovich TJ, Mahan AE, Liao L, Streeck H, Andrews C, Rerks-Ngarm S, Nitayaphan S, de Souza MS, Kaewkungwal J, Pitisuttithum P, Francis D, Michael NL, Kim JH, Bailey-Kellogg C, Ackerman ME, Alter G. Chung AW, et al. Among authors: dugast as. Sci Transl Med. 2014 Mar 19;6(228):228ra38. doi: 10.1126/scitranslmed.3007736. Sci Transl Med. 2014. PMID: 24648341
Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complement.
Lofano G, Gorman MJ, Yousif AS, Yu WH, Fox JM, Dugast AS, Ackerman ME, Suscovich TJ, Weiner J, Barouch D, Streeck H, Little S, Smith D, Richman D, Lauffenburger D, Walker BD, Diamond MS, Alter G. Lofano G, et al. Among authors: dugast as. Sci Immunol. 2018 Aug 17;3(26):eaat7796. doi: 10.1126/sciimmunol.aat7796. Sci Immunol. 2018. PMID: 30120121 Free PMC article.
Decreased Fc receptor expression on innate immune cells is associated with impaired antibody-mediated cellular phagocytic activity in chronically HIV-1 infected individuals.
Dugast AS, Tonelli A, Berger CT, Ackerman ME, Sciaranghella G, Liu Q, Sips M, Toth I, Piechocka-Trocha A, Ghebremichael M, Alter G. Dugast AS, et al. Virology. 2011 Jul 5;415(2):160-7. doi: 10.1016/j.virol.2011.03.012. Epub 2011 May 12. Virology. 2011. PMID: 21565376 Free PMC article.
Distinct Immunoglobulin Fc Glycosylation Patterns Are Associated with Disease Nonprogression and Broadly Neutralizing Antibody Responses in Children with HIV Infection.
Muenchhoff M, Chung AW, Roider J, Dugast AS, Richardson S, Kløverpris H, Leslie A, Ndung'u T, Moore P, Alter G, Goulder PJR. Muenchhoff M, et al. Among authors: dugast as. mSphere. 2020 Dec 23;5(6):e00880-20. doi: 10.1128/mSphere.00880-20. mSphere. 2020. PMID: 33361123 Free PMC article.
41 results