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Urokinase-type plasminogen activator receptor (uPAR) ligation induces a raft-localized integrin signaling switch that mediates the hypermotile phenotype of fibrotic fibroblasts.
Grove LM, Southern BD, Jin TH, White KE, Paruchuri S, Harel E, Wei Y, Rahaman SO, Gladson CL, Ding Q, Craik CS, Chapman HA, Olman MA. Grove LM, et al. Among authors: olman ma. J Biol Chem. 2014 May 2;289(18):12791-804. doi: 10.1074/jbc.M113.498576. Epub 2014 Mar 18. J Biol Chem. 2014. PMID: 24644284 Free PMC article.
Matrix-driven Myosin II Mediates the Pro-fibrotic Fibroblast Phenotype.
Southern BD, Grove LM, Rahaman SO, Abraham S, Scheraga RG, Niese KA, Sun H, Herzog EL, Liu F, Tschumperlin DJ, Egelhoff TT, Rosenfeld SS, Olman MA. Southern BD, et al. Among authors: olman ma. J Biol Chem. 2016 Mar 18;291(12):6083-95. doi: 10.1074/jbc.M115.712380. Epub 2016 Jan 13. J Biol Chem. 2016. PMID: 26763235 Free PMC article.
Urokinase receptor mediates lung fibroblast attachment and migration toward provisional matrix proteins through interaction with multiple integrins.
Zhu S, Gladson CL, White KE, Ding Q, Stewart J Jr, Jin TH, Chapman HA Jr, Olman MA. Zhu S, et al. Among authors: olman ma. Am J Physiol Lung Cell Mol Physiol. 2009 Jul;297(1):L97-108. doi: 10.1152/ajplung.90283.2008. Epub 2009 May 1. Am J Physiol Lung Cell Mol Physiol. 2009. PMID: 19411312 Free PMC article.
FAK-related nonkinase is a multifunctional negative regulator of pulmonary fibrosis.
Ding Q, Cai GQ, Hu M, Yang Y, Zheng A, Tang Q, Gladson CL, Hayasaka H, Wu H, You Z, Southern BD, Grove LM, Rahaman SO, Fang H, Olman MA. Ding Q, et al. Among authors: olman ma. Am J Pathol. 2013 May;182(5):1572-84. doi: 10.1016/j.ajpath.2013.01.026. Epub 2013 Mar 14. Am J Pathol. 2013. PMID: 23499373 Free PMC article.
85 results