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Urokinase-type plasminogen activator receptor (uPAR) ligation induces a raft-localized integrin signaling switch that mediates the hypermotile phenotype of fibrotic fibroblasts.
Grove LM, Southern BD, Jin TH, White KE, Paruchuri S, Harel E, Wei Y, Rahaman SO, Gladson CL, Ding Q, Craik CS, Chapman HA, Olman MA. Grove LM, et al. Among authors: chapman ha. J Biol Chem. 2014 May 2;289(18):12791-804. doi: 10.1074/jbc.M113.498576. Epub 2014 Mar 18. J Biol Chem. 2014. PMID: 24644284 Free PMC article.
Urokinase receptor and integrin interactions.
Kugler MC, Wei Y, Chapman HA. Kugler MC, et al. Among authors: chapman ha. Curr Pharm Des. 2003;9(19):1565-74. doi: 10.2174/1381612033454658. Curr Pharm Des. 2003. PMID: 12871068 Review.
Urokinase receptor mediates lung fibroblast attachment and migration toward provisional matrix proteins through interaction with multiple integrins.
Zhu S, Gladson CL, White KE, Ding Q, Stewart J Jr, Jin TH, Chapman HA Jr, Olman MA. Zhu S, et al. Among authors: chapman ha jr. Am J Physiol Lung Cell Mol Physiol. 2009 Jul;297(1):L97-108. doi: 10.1152/ajplung.90283.2008. Epub 2009 May 1. Am J Physiol Lung Cell Mol Physiol. 2009. PMID: 19411312 Free PMC article.
212 results