Wang Z - Search Results

1

Human UGT1A4 and UGT1A3 conjugate 25-hydroxyvitamin D3: metabolite structure, kinetics, inducibility, and interindividual variability.

Wang Z, Wong T, Hashizume T, Dickmann LZ, Scian M, Koszewski NJ, Goff JP, Horst RL, Chaudhry AS, Schuetz EG, Thummel KE. Wang Z, et al. Endocrinology. 2014 Jun;155(6):2052-63. doi: 10.1210/en.2013-2013. Epub 2014 Mar 18. Endocrinology. 2014. PMID: 24641623 Free PMC article.

2

Polymorphic Human Sulfotransferase 2A1 Mediates the Formation of 25-Hydroxyvitamin D₃-3-O-Sulfate, a Major Circulating Vitamin D Metabolite in Humans.

Wong T, Wang Z, Chapron BD, Suzuki M, Claw KG, Gao C, Foti RS, Prasad B, Chapron A, Calamia J, Chaudhry A, Schuetz EG, Horst RL, Mao Q, de Boer IH, Thornton TA, Thummel KE. Wong T, et al. Among authors: wang z. Drug Metab Dispos. 2018 Apr;46(4):367-379. doi: 10.1124/dmd.117.078428. Epub 2018 Jan 17. Drug Metab Dispos. 2018. PMID: 29343609 Free PMC article.

3

An inducible cytochrome P450 3A4-dependent vitamin D catabolic pathway.

Wang Z, Lin YS, Zheng XE, Senn T, Hashizume T, Scian M, Dickmann LJ, Nelson SD, Baillie TA, Hebert MF, Blough D, Davis CL, Thummel KE. Wang Z, et al. Mol Pharmacol. 2012 Apr;81(4):498-509. doi: 10.1124/mol.111.076356. Epub 2011 Dec 28. Mol Pharmacol. 2012. PMID: 22205755 Free PMC article.

4

Enhancement of hepatic 4-hydroxylation of 25-hydroxyvitamin D3 through CYP3A4 induction in vitro and in vivo: implications for drug-induced osteomalacia.

Wang Z, Lin YS, Dickmann LJ, Poulton EJ, Eaton DL, Lampe JW, Shen DD, Davis CL, Shuhart MC, Thummel KE. Wang Z, et al. J Bone Miner Res. 2013 May;28(5):1101-16. doi: 10.1002/jbmr.1839. J Bone Miner Res. 2013. PMID: 23212742 Free PMC article.

5

Simultaneous quantification of 25-hydroxyvitamin D₃-3-sulfate and 25-hydroxyvitamin D₃-3-glucuronide in human serum and plasma using liquid chromatography-tandem mass spectrometry coupled with DAPTAD-derivatization.

Gao C, Bergagnini-Kolev MC, Liao MZ, Wang Z, Wong T, Calamia JC, Lin YS, Mao Q, Thummel KE. Gao C, et al. Among authors: wang z. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Aug 15;1060:158-165. doi: 10.1016/j.jchromb.2017.06.017. Epub 2017 Jun 9. J Chromatogr B Analyt Technol Biomed Life Sci. 2017. PMID: 28622619 Free PMC article.

6

Human PXR-mediated induction of intestinal CYP3A4 attenuates 1α,25-dihydroxyvitamin D₃ function in human colon adenocarcinoma LS180 cells.

Zheng XE, Wang Z, Liao MZ, Lin YS, Shuhart MC, Schuetz EG, Thummel KE. Zheng XE, et al. Among authors: wang z. Biochem Pharmacol. 2012 Aug 1;84(3):391-401. doi: 10.1016/j.bcp.2012.04.019. Epub 2012 May 4. Biochem Pharmacol. 2012. PMID: 22562045 Free PMC article.

7

Interplay between vitamin D and the drug metabolizing enzyme CYP3A4.

Wang Z, Schuetz EG, Xu Y, Thummel KE. Wang Z, et al. J Steroid Biochem Mol Biol. 2013 Jul;136:54-8. doi: 10.1016/j.jsbmb.2012.09.012. Epub 2012 Sep 15. J Steroid Biochem Mol Biol. 2013. PMID: 22985909 Free PMC article. Review.

8

Differential Effects of Oral Boluses of Vitamin D2 vs Vitamin D3 on Vitamin D Metabolism: A Randomized Controlled Trial.

Martineau AR, Thummel KE, Wang Z, Jolliffe DA, Boucher BJ, Griffin SJ, Forouhi NG, Hitman GA. Martineau AR, et al. Among authors: wang z. J Clin Endocrinol Metab. 2019 Dec 1;104(12):5831-5839. doi: 10.1210/jc.2019-00207. J Clin Endocrinol Metab. 2019. PMID: 31199458 Free PMC article. Clinical Trial.

9

Characterizing antibody cross-reactivity for immunoaffinity purification of analytes prior to multiplexed liquid chromatography-tandem mass spectrometry.

Laha TJ, Strathmann FG, Wang Z, de Boer IH, Thummel KE, Hoofnagle AN. Laha TJ, et al. Among authors: wang z. Clin Chem. 2012 Dec;58(12):1711-6. doi: 10.1373/clinchem.2012.185827. Epub 2012 Sep 11. Clin Chem. 2012. PMID: 22968104 Free PMC article.

10

Functional Comparison of Human Colonic Carcinoma Cell Lines and Primary Small Intestinal Epithelial Cells for Investigations of Intestinal Drug Permeability and First-Pass Metabolism.

Yamaura Y, Chapron BD, Wang Z, Himmelfarb J, Thummel KE. Yamaura Y, et al. Among authors: wang z. Drug Metab Dispos. 2016 Mar;44(3):329-35. doi: 10.1124/dmd.115.068429. Epub 2015 Dec 23. Drug Metab Dispos. 2016. PMID: 26700954 Free PMC article.

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