Rosati S - Search Results

1

Complement is activated by IgG hexamers assembled at the cell surface.

Diebolder CA, Beurskens FJ, de Jong RN, Koning RI, Strumane K, Lindorfer MA, Voorhorst M, Ugurlar D, Rosati S, Heck AJ, van de Winkel JG, Wilson IA, Koster AJ, Taylor RP, Saphire EO, Burton DR, Schuurman J, Gros P, Parren PW. Diebolder CA, et al. Among authors: rosati s. Science. 2014 Mar 14;343(6176):1260-3. doi: 10.1126/science.1248943. Science. 2014. PMID: 24626930 Free PMC article.

2

Performing native mass spectrometry analysis on therapeutic antibodies.

Thompson NJ, Rosati S, Heck AJ. Thompson NJ, et al. Among authors: rosati s. Methods. 2014 Jan 1;65(1):11-7. doi: 10.1016/j.ymeth.2013.05.003. Epub 2013 May 18. Methods. 2014. PMID: 23688935

3

In-depth qualitative and quantitative analysis of composite glycosylation profiles and other micro-heterogeneity on intact monoclonal antibodies by high-resolution native mass spectrometry using a modified Orbitrap.

Rosati S, van den Bremer ET, Schuurman J, Parren PW, Kamerling JP, Heck AJ. Rosati S, et al. MAbs. 2013 Nov-Dec;5(6):917-24. doi: 10.4161/mabs.26282. Epub 2013 Aug 28. MAbs. 2013. PMID: 23995615 Free PMC article.

4

Exploring an orbitrap analyzer for the characterization of intact antibodies by native mass spectrometry.

Rosati S, Rose RJ, Thompson NJ, van Duijn E, Damoc E, Denisov E, Makarov A, Heck AJ. Rosati S, et al. Angew Chem Int Ed Engl. 2012 Dec 21;51(52):12992-6. doi: 10.1002/anie.201206745. Epub 2012 Nov 22. Angew Chem Int Ed Engl. 2012. PMID: 23172610

5

The impact of mass spectrometry on the study of intact antibodies: from post-translational modifications to structural analysis.

Thompson NJ, Rosati S, Rose RJ, Heck AJ. Thompson NJ, et al. Among authors: rosati s. Chem Commun (Camb). 2013 Jan 21;49(6):538-48. doi: 10.1039/c2cc36755f. Epub 2012 Nov 26. Chem Commun (Camb). 2013. PMID: 23183499

6

Detailed mass analysis of structural heterogeneity in monoclonal antibodies using native mass spectrometry.

Rosati S, Yang Y, Barendregt A, Heck AJ. Rosati S, et al. Nat Protoc. 2014 Apr;9(4):967-76. doi: 10.1038/nprot.2014.057. Epub 2014 Mar 27. Nat Protoc. 2014. PMID: 24675736

7

Phosphorylation dependence and stoichiometry of the complex formed by tyrosine hydroxylase and 14-3-3γ.

Kleppe R, Rosati S, Jorge-Finnigan A, Alvira S, Ghorbani S, Haavik J, Valpuesta JM, Heck AJ, Martinez A. Kleppe R, et al. Among authors: rosati s. Mol Cell Proteomics. 2014 Aug;13(8):2017-30. doi: 10.1074/mcp.M113.035709. Epub 2014 Jun 19. Mol Cell Proteomics. 2014. PMID: 24947669 Free PMC article.

8

Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.

Helbig AO, Rosati S, Pijnappel PW, van Breukelen B, Timmers MH, Mohammed S, Slijper M, Heck AJ. Helbig AO, et al. Among authors: rosati s. BMC Genomics. 2010 Dec 2;11:685. doi: 10.1186/1471-2164-11-685. BMC Genomics. 2010. PMID: 21126336 Free PMC article.

9

Qualitative and semiquantitative analysis of composite mixtures of antibodies by native mass spectrometry.

Rosati S, Thompson NJ, Barendregt A, Hendriks LJ, Bakker AB, de Kruif J, Throsby M, van Duijn E, Heck AJ. Rosati S, et al. Anal Chem. 2012 Aug 21;84(16):7227-32. doi: 10.1021/ac301611d. Epub 2012 Aug 10. Anal Chem. 2012. PMID: 22882109

10

Precursor of ether phospholipids is synthesized by a flavoenzyme through covalent catalysis.

Nenci S, Piano V, Rosati S, Aliverti A, Pandini V, Fraaije MW, Heck AJ, Edmondson DE, Mattevi A. Nenci S, et al. Among authors: rosati s. Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):18791-6. doi: 10.1073/pnas.1215128109. Epub 2012 Oct 29. Proc Natl Acad Sci U S A. 2012. PMID: 23112191 Free PMC article.

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