Lau AA - Search Results

1

A simple method for early age phenotype confirmation using toe tissue from a mouse model of MPS IIIA.

Trim PJ, Lau AA, Hopwood JJ, Snel MF. Trim PJ, et al. Among authors: lau aa. Rapid Commun Mass Spectrom. 2014 Apr 30;28(8):933-8. doi: 10.1002/rcm.6861. Rapid Commun Mass Spectrom. 2014. PMID: 24623698

2

In vitro characterization of genetically modified embryonic stem cells as a therapy for murine mucopolysaccharidosis type IIIA.

Lau AA, Hemsley KM, Meedeniya A, Hopwood JJ. Lau AA, et al. Mol Genet Metab. 2004 Feb;81(2):86-95. doi: 10.1016/j.ymgme.2003.11.007. Mol Genet Metab. 2004. PMID: 14741188

3

Directed differentiation and characterization of genetically modified embryonic stem cells for therapy.

Lau AA, Hemsley KM, Meedeniya A, Robinson AJ, Hopwood JJ. Lau AA, et al. Methods Mol Biol. 2006;329:471-84. doi: 10.1385/1-59745-037-5:471. Methods Mol Biol. 2006. PMID: 16846011

4

Functional correction of CNS lesions in an MPS-IIIA mouse model by intracerebral AAV-mediated delivery of sulfamidase and SUMF1 genes.

Fraldi A, Hemsley K, Crawley A, Lombardi A, Lau A, Sutherland L, Auricchio A, Ballabio A, Hopwood JJ. Fraldi A, et al. Hum Mol Genet. 2007 Nov 15;16(22):2693-702. doi: 10.1093/hmg/ddm223. Epub 2007 Aug 27. Hum Mol Genet. 2007. PMID: 17725987

5

Open field locomotor activity and anxiety-related behaviors in mucopolysaccharidosis type IIIA mice.

Lau AA, Crawley AC, Hopwood JJ, Hemsley KM. Lau AA, et al. Behav Brain Res. 2008 Aug 5;191(1):130-6. doi: 10.1016/j.bbr.2008.03.024. Epub 2008 Mar 25. Behav Brain Res. 2008. PMID: 18453006

6

SGSH gene transfer in mucopolysaccharidosis type IIIA mice using canine adenovirus vectors.

Lau AA, Hopwood JJ, Kremer EJ, Hemsley KM. Lau AA, et al. Mol Genet Metab. 2010 Jun;100(2):168-75. doi: 10.1016/j.ymgme.2010.02.006. Epub 2010 Feb 14. Mol Genet Metab. 2010. PMID: 20231109

7

Allogeneic stem cell transplantation does not improve neurological deficits in mucopolysaccharidosis type IIIA mice.

Lau AA, Hannouche H, Rozaklis T, Hassiotis S, Hopwood JJ, Hemsley KM. Lau AA, et al. Exp Neurol. 2010 Oct;225(2):445-54. doi: 10.1016/j.expneurol.2010.07.024. Epub 2010 Jul 27. Exp Neurol. 2010. PMID: 20673764

8

Helper-dependent canine adenovirus vector-mediated transgene expression in a neurodegenerative lysosomal storage disorder.

Lau AA, Rozaklis T, Ibanes S, Luck AJ, Beard H, Hassiotis S, Mazouni K, Hopwood JJ, Kremer EJ, Hemsley KM. Lau AA, et al. Gene. 2012 Jan 1;491(1):53-7. doi: 10.1016/j.gene.2011.09.004. Epub 2011 Sep 22. Gene. 2012. PMID: 21963444

9

Neonatal Bone Marrow Transplantation in MPS IIIA Mice.

Lau AA, Shamsani NJ, Winner LK, Hassiotis S, King BM, Hopwood JJ, Hemsley KM. Lau AA, et al. JIMD Rep. 2013;8:121-32. doi: 10.1007/8904_2012_169. Epub 2012 Aug 10. JIMD Rep. 2013. PMID: 23430528 Free PMC article.

10

A Preclinical Study Evaluating AAVrh10-Based Gene Therapy for Sanfilippo Syndrome.

Winner LK, Beard H, Hassiotis S, Lau AA, Luck AJ, Hopwood JJ, Hemsley KM. Winner LK, et al. Among authors: lau aa. Hum Gene Ther. 2016 May;27(5):363-75. doi: 10.1089/hum.2015.170. Hum Gene Ther. 2016. PMID: 26975339

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