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Chiral cyclopalladated complexes derived from N,N-dimethyl-1-phenethylamine with bridging bis(diphenylphosphine)ferrocene ligand as inhibitors of the cathepsin B activity and as antitumoral agents.
Bincoletto C, Tersariol IL, Oliveira CR, Dreher S, Fausto DM, Soufen MA, Nascimento FD, Caires AC. Bincoletto C, et al. Among authors: nascimento fd. Bioorg Med Chem. 2005 Apr 15;13(8):3047-55. doi: 10.1016/j.bmc.2005.01.057. Bioorg Med Chem. 2005. PMID: 15781414
Cathepsin X binds to cell surface heparan sulfate proteoglycans.
Nascimento FD, Rizzi CC, Nantes IL, Stefe I, Turk B, Carmona AK, Nader HB, Juliano L, Tersariol IL. Nascimento FD, et al. Arch Biochem Biophys. 2005 Apr 15;436(2):323-32. doi: 10.1016/j.abb.2005.01.013. Arch Biochem Biophys. 2005. PMID: 15797245
Pre-clinical antitumour evaluation of Biphosphinic Palladacycle Complex in human leukaemia cells.
Oliveira CR, Barbosa CM, Nascimento FD, Lanetzki CS, Meneghin MB, Pereira FE, Paredes-Gamero EJ, Ferreira AT, Rodrigues T, Queiroz ML, Caires AC, Tersariol IL, Bincoletto C. Oliveira CR, et al. Among authors: nascimento fd. Chem Biol Interact. 2009 Feb 12;177(3):181-9. doi: 10.1016/j.cbi.2008.10.034. Epub 2008 Nov 5. Chem Biol Interact. 2009. PMID: 19026616
72 results