Copple B - Search Results

1

E2F1 is a novel fibrogenic gene that regulates cholestatic liver fibrosis through the Egr-1/SHP/EID1 network.

Zhang Y, Xu N, Xu J, Kong B, Copple B, Guo GL, Wang L. Zhang Y, et al. Among authors: copple b. Hepatology. 2014 Sep;60(3):919-30. doi: 10.1002/hep.27121. Epub 2014 Jul 25. Hepatology. 2014. PMID: 24619556 Free PMC article.

2

Fibrinogen deficiency increases liver injury and early growth response-1 (Egr-1) expression in a model of chronic xenobiotic-induced cholestasis.

Luyendyk JP, Kassel KM, Allen K, Guo GL, Li G, Cantor GH, Copple BL. Luyendyk JP, et al. Am J Pathol. 2011 Mar;178(3):1117-25. doi: 10.1016/j.ajpath.2010.11.064. Am J Pathol. 2011. PMID: 21356363 Free PMC article.

3

Nrf2 promotes the development of fibrosis and tumorigenesis in mice with defective hepatic autophagy.

Ni HM, Woolbright BL, Williams J, Copple B, Cui W, Luyendyk JP, Jaeschke H, Ding WX. Ni HM, et al. Among authors: copple b. J Hepatol. 2014 Sep;61(3):617-25. doi: 10.1016/j.jhep.2014.04.043. Epub 2014 May 9. J Hepatol. 2014. PMID: 24815875 Free PMC article.

4

Early growth response factor-1 is critical for cholestatic liver injury.

Kim ND, Moon JO, Slitt AL, Copple BL. Kim ND, et al. Toxicol Sci. 2006 Apr;90(2):586-95. doi: 10.1093/toxsci/kfj111. Epub 2006 Jan 19. Toxicol Sci. 2006. PMID: 16423862

5

Hypoxia-inducible factor activation in myeloid cells contributes to the development of liver fibrosis in cholestatic mice.

Copple BL, Kaska S, Wentling C. Copple BL, et al. J Pharmacol Exp Ther. 2012 May;341(2):307-16. doi: 10.1124/jpet.111.189340. Epub 2012 Jan 23. J Pharmacol Exp Ther. 2012. PMID: 22271822 Free PMC article.

6

Tissue factor-dependent coagulation contributes to alpha-naphthylisothiocyanate-induced cholestatic liver injury in mice.

Luyendyk JP, Cantor GH, Kirchhofer D, Mackman N, Copple BL, Wang R. Luyendyk JP, et al. Am J Physiol Gastrointest Liver Physiol. 2009 Apr;296(4):G840-9. doi: 10.1152/ajpgi.90639.2008. Epub 2009 Jan 29. Am J Physiol Gastrointest Liver Physiol. 2009. PMID: 19179621 Free PMC article.

7

Early growth response factor-1 limits biliary fibrosis in a model of xenobiotic-induced cholestasis in mice.

Sullivan BP, Cui W, Copple BL, Luyendyk JP. Sullivan BP, et al. Toxicol Sci. 2012 Mar;126(1):267-74. doi: 10.1093/toxsci/kfr311. Epub 2011 Nov 17. Toxicol Sci. 2012. PMID: 22094456 Free PMC article.

8

Role of hypoxia inducing factor-1β in alcohol-induced autophagy, steatosis and liver injury in mice.

Ni HM, Bhakta A, Wang S, Li Z, Manley S, Huang H, Copple B, Ding WX. Ni HM, et al. Among authors: copple b. PLoS One. 2014 Dec 23;9(12):e115849. doi: 10.1371/journal.pone.0115849. eCollection 2014. PLoS One. 2014. PMID: 25536043 Free PMC article.

9

Bile acids induce inflammatory genes in hepatocytes: a novel mechanism of inflammation during obstructive cholestasis.

Allen K, Jaeschke H, Copple BL. Allen K, et al. Am J Pathol. 2011 Jan;178(1):175-86. doi: 10.1016/j.ajpath.2010.11.026. Epub 2010 Dec 23. Am J Pathol. 2011. PMID: 21224055 Free PMC article.

10

Hepatic stellate cells orchestrate clearance of necrotic cells in a hypoxia-inducible factor-1α-dependent manner by modulating macrophage phenotype in mice.

Mochizuki A, Pace A, Rockwell CE, Roth KJ, Chow A, O'Brien KM, Albee R, Kelly K, Towery K, Luyendyk JP, Copple BL. Mochizuki A, et al. J Immunol. 2014 Apr 15;192(8):3847-3857. doi: 10.4049/jimmunol.1303195. Epub 2014 Mar 17. J Immunol. 2014. PMID: 24639359 Free PMC article.

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