Yang C - Search Results

1

Partial loss of TDP-43 function causes phenotypes of amyotrophic lateral sclerosis.

Yang C, Wang H, Qiao T, Yang B, Aliaga L, Qiu L, Tan W, Salameh J, McKenna-Yasek DM, Smith T, Peng L, Moore MJ, Brown RH Jr, Cai H, Xu Z. Yang C, et al. Among authors: yang b. Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):E1121-9. doi: 10.1073/pnas.1322641111. Epub 2014 Mar 10. Proc Natl Acad Sci U S A. 2014. PMID: 24616503 Free PMC article.

2

Widespread spinal cord transduction by intrathecal injection of rAAV delivers efficacious RNAi therapy for amyotrophic lateral sclerosis.

Wang H, Yang B, Qiu L, Yang C, Kramer J, Su Q, Guo Y, Brown RH Jr, Gao G, Xu Z. Wang H, et al. Among authors: yang c, yang b. Hum Mol Genet. 2014 Feb 1;23(3):668-81. doi: 10.1093/hmg/ddt454. Epub 2013 Sep 18. Hum Mol Genet. 2014. PMID: 24108104 Free PMC article.

3

TDP-43-The key to understanding amyotrophic lateral sclerosis.

Xu Z, Yang C. Xu Z, et al. Among authors: yang c. Rare Dis. 2014 Oct 30;2(1):e944443. doi: 10.4161/21675511.2014.944443. eCollection 2014. Rare Dis. 2014. PMID: 26942097 Free PMC article.

4

Mutant PFN1 causes ALS phenotypes and progressive motor neuron degeneration in mice by a gain of toxicity.

Yang C, Danielson EW, Qiao T, Metterville J, Brown RH Jr, Landers JE, Xu Z. Yang C, et al. Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6209-E6218. doi: 10.1073/pnas.1605964113. Epub 2016 Sep 28. Proc Natl Acad Sci U S A. 2016. PMID: 27681617 Free PMC article.

5

Low-level overexpression of wild type TDP-43 causes late-onset, progressive neurodegeneration and paralysis in mice.

Yang C, Qiao T, Yu J, Wang H, Guo Y, Salameh J, Metterville J, Parsi S, Yusuf I, Brown RH, Cai H, Xu Z. Yang C, et al. PLoS One. 2022 Feb 3;17(2):e0255710. doi: 10.1371/journal.pone.0255710. eCollection 2022. PLoS One. 2022. PMID: 35113871 Free PMC article.

6

The C-terminal TDP-43 fragments have a high aggregation propensity and harm neurons by a dominant-negative mechanism.

Yang C, Tan W, Whittle C, Qiu L, Cao L, Akbarian S, Xu Z. Yang C, et al. PLoS One. 2010 Dec 31;5(12):e15878. doi: 10.1371/journal.pone.0015878. PLoS One. 2010. PMID: 21209826 Free PMC article.

7

Specific gene silencing using RNAi in cell culture.

Yang C, Qiu L, Xu Z. Yang C, et al. Methods Mol Biol. 2011;793:457-77. doi: 10.1007/978-1-61779-328-8_30. Methods Mol Biol. 2011. PMID: 21913119 Free PMC article.

8

A Single Injection of Recombinant Adeno-Associated Virus into the Lumbar Cistern Delivers Transgene Expression Throughout the Whole Spinal Cord.

Guo Y, Wang D, Qiao T, Yang C, Su Q, Gao G, Xu Z. Guo Y, et al. Among authors: yang c. Mol Neurobiol. 2016 Jul;53(5):3235-3248. doi: 10.1007/s12035-015-9223-1. Epub 2015 Jun 7. Mol Neurobiol. 2016. PMID: 26050084 Free PMC article.

9

Slow Intrathecal Injection of rAAVrh10 Enhances its Transduction of Spinal Cord and Therapeutic Efficacy in a Mutant SOD1 Model of ALS.

Li D, Liu C, Yang C, Wang D, Wu D, Qi Y, Su Q, Gao G, Xu Z, Guo Y. Li D, et al. Among authors: yang c. Neuroscience. 2017 Dec 4;365:192-205. doi: 10.1016/j.neuroscience.2017.10.001. Epub 2017 Oct 9. Neuroscience. 2017. PMID: 29024785 Free PMC article.

10

Bufalin Ameliorates Myocardial Ischemia/Reperfusion Injury by Suppressing Macrophage Pyroptosis via P62 Pathway.

Li C, Ma Z, Wei X, Wang Y, Wu J, Li X, Sun X, Ding Z, Yang C, Zou Y. Li C, et al. Among authors: yang c. J Cardiovasc Transl Res. 2024 Dec 28. doi: 10.1007/s12265-024-10577-9. Online ahead of print. J Cardiovasc Transl Res. 2024. PMID: 39733202

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