Sahin G - Search Results

1

Differential dopamine receptor occupancy underlies L-DOPA-induced dyskinesia in a rat model of Parkinson's disease.

Sahin G, Thompson LH, Lavisse S, Ozgur M, Rbah-Vidal L, Dollé F, Hantraye P, Kirik D. Sahin G, et al. PLoS One. 2014 Mar 10;9(3):e90759. doi: 10.1371/journal.pone.0090759. eCollection 2014. PLoS One. 2014. PMID: 24614598 Free PMC article.

2

Presynaptic dopaminergic compartment determines the susceptibility to L-DOPA-induced dyskinesia in rats.

Ulusoy A, Sahin G, Kirik D. Ulusoy A, et al. Among authors: sahin g. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13159-64. doi: 10.1073/pnas.1003432107. Epub 2010 Jul 6. Proc Natl Acad Sci U S A. 2010. PMID: 20615977 Free PMC article.

3

Key factors determining the efficacy of gene therapy for continuous DOPA delivery in the Parkinsonian brain.

Cederfjäll E, Sahin G, Kirik D. Cederfjäll E, et al. Among authors: sahin g. Neurobiol Dis. 2012 Nov;48(2):222-7. doi: 10.1016/j.nbd.2011.10.017. Epub 2011 Oct 25. Neurobiol Dis. 2012. PMID: 22048069 Review.

4

Design of a single AAV vector for coexpression of TH and GCH1 to establish continuous DOPA synthesis in a rat model of Parkinson's disease.

Cederfjäll E, Sahin G, Kirik D, Björklund T. Cederfjäll E, et al. Among authors: sahin g. Mol Ther. 2012 Jul;20(7):1315-26. doi: 10.1038/mt.2012.1. Epub 2012 Jan 31. Mol Ther. 2012. PMID: 22294150 Free PMC article.

5

Continuous DOPA synthesis from a single AAV: dosing and efficacy in models of Parkinson's disease.

Cederfjäll E, Nilsson N, Sahin G, Chu Y, Nikitidou E, Björklund T, Kordower JH, Kirik D. Cederfjäll E, et al. Among authors: sahin g. Sci Rep. 2013;3:2157. doi: 10.1038/srep02157. Sci Rep. 2013. PMID: 23831692 Free PMC article.

6

Dose optimization for long-term rAAV-mediated RNA interference in the nigrostriatal projection neurons.

Ulusoy A, Sahin G, Björklund T, Aebischer P, Kirik D. Ulusoy A, et al. Among authors: sahin g. Mol Ther. 2009 Sep;17(9):1574-84. doi: 10.1038/mt.2009.142. Epub 2009 Jul 7. Mol Ther. 2009. PMID: 19584816 Free PMC article.

7

Functional convergence of dopaminergic and cholinergic input is critical for hippocampus-dependent working memory.

Wisman LA, Sahin G, Maingay M, Leanza G, Kirik D. Wisman LA, et al. Among authors: sahin g. J Neurosci. 2008 Jul 30;28(31):7797-807. doi: 10.1523/JNEUROSCI.1885-08.2008. J Neurosci. 2008. PMID: 18667612 Free PMC article.

8

Ser129D mutant alpha-synuclein induces earlier motor dysfunction while S129A results in distinctive pathology in a rat model of Parkinson's disease.

Febbraro F, Sahin G, Farran A, Soares S, Jensen PH, Kirik D, Romero-Ramos M. Febbraro F, et al. Among authors: sahin g. Neurobiol Dis. 2013 Aug;56:47-58. doi: 10.1016/j.nbd.2013.03.014. Epub 2013 Apr 5. Neurobiol Dis. 2013. PMID: 23567651

9

α-Synuclein expression and Nrf2 deficiency cooperate to aggravate protein aggregation, neuronal death and inflammation in early-stage Parkinson's disease.

Lastres-Becker I, Ulusoy A, Innamorato NG, Sahin G, Rábano A, Kirik D, Cuadrado A. Lastres-Becker I, et al. Among authors: sahin g. Hum Mol Genet. 2012 Jul 15;21(14):3173-92. doi: 10.1093/hmg/dds143. Epub 2012 Apr 18. Hum Mol Genet. 2012. PMID: 22513881

10

Neuroinflammation in Parkinson's Disease and its Treatment Opportunities.

Çınar E, Tel BC, Şahin G. Çınar E, et al. Among authors: sahin g. Balkan Med J. 2022 Sep 9;39(5):318-333. doi: 10.4274/balkanmedj.galenos.2022.2022-7-100. Epub 2022 Aug 29. Balkan Med J. 2022. PMID: 36036436 Free PMC article.

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