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Investigating mitochondrial metabolism in contracting HL-1 cardiomyocytes following hypoxia and pharmacological HIF activation identifies HIF-dependent and independent mechanisms of regulation.
Ambrose LJ, Abd-Jamil AH, Gomes RS, Carter EE, Carr CA, Clarke K, Heather LC. Ambrose LJ, et al. Among authors: heather lc. J Cardiovasc Pharmacol Ther. 2014 Nov;19(6):574-85. doi: 10.1177/1074248414524480. Epub 2014 Mar 7. J Cardiovasc Pharmacol Ther. 2014. PMID: 24607765
Compartmentalization proteomics revealed endolysosomal protein network changes in a goat model of atrial fibrillation.
Ayagama T, Charles PD, Bose SJ, Boland B, Priestman DA, Aston D, Berridge G, Fischer R, Cribbs AP, Song Q, Mirams GR, Amponsah K, Heather L, Galione A, Herring N, Kramer H, Capel RA, Platt FM, Schotten U, Verheule S, Burton RAB. Ayagama T, et al. iScience. 2024 Mar 28;27(6):109609. doi: 10.1016/j.isci.2024.109609. eCollection 2024 Jun 21. iScience. 2024. PMID: 38827406 Free PMC article.
Dysregulation of hypoxia pathways in fumarate hydratase-deficient cells is independent of defective mitochondrial metabolism.
O'Flaherty L, Adam J, Heather LC, Zhdanov AV, Chung YL, Miranda MX, Croft J, Olpin S, Clarke K, Pugh CW, Griffiths J, Papkovsky D, Ashrafian H, Ratcliffe PJ, Pollard PJ. O'Flaherty L, et al. Among authors: heather lc. Hum Mol Genet. 2010 Oct 1;19(19):3844-51. doi: 10.1093/hmg/ddq305. Epub 2010 Jul 21. Hum Mol Genet. 2010. PMID: 20660115 Free PMC article.
62 results