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Collagen breaks at weak sacrificial bonds taming its mechanoradicals.
Rennekamp B, Karfusehr C, Kurth M, Ünal A, Monego D, Riedmiller K, Gryn'ova G, Hudson DM, Gräter F. Rennekamp B, et al. Among authors: grater f. Nat Commun. 2023 Apr 12;14(1):2075. doi: 10.1038/s41467-023-37726-z. Nat Commun. 2023. PMID: 37045839 Free PMC article.
Shear-induced unfolding activates von Willebrand factor A2 domain for proteolysis.
Baldauf C, Schneppenheim R, Stacklies W, Obser T, Pieconka A, Schneppenheim S, Budde U, Zhou J, Gräter F. Baldauf C, et al. Among authors: grater f. J Thromb Haemost. 2009 Dec;7(12):2096-105. doi: 10.1111/j.1538-7836.2009.03640.x. Epub 2009 Oct 8. J Thromb Haemost. 2009. PMID: 19817991 Free article.
von Willebrand factor directly interacts with DNA from neutrophil extracellular traps.
Grässle S, Huck V, Pappelbaum KI, Gorzelanny C, Aponte-Santamaría C, Baldauf C, Gräter F, Schneppenheim R, Obser T, Schneider SW. Grässle S, et al. Among authors: grater f. Arterioscler Thromb Vasc Biol. 2014 Jul;34(7):1382-9. doi: 10.1161/ATVBAHA.113.303016. Epub 2014 May 1. Arterioscler Thromb Vasc Biol. 2014. PMID: 24790143
Mechanism of Focal Adhesion Kinase Mechanosensing.
Zhou J, Aponte-Santamaría C, Sturm S, Bullerjahn JT, Bronowska A, Gräter F. Zhou J, et al. Among authors: grater f. PLoS Comput Biol. 2015 Nov 6;11(11):e1004593. doi: 10.1371/journal.pcbi.1004593. eCollection 2015 Nov. PLoS Comput Biol. 2015. PMID: 26544178 Free PMC article.
132 results