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In vitro and in vivo studies of the biological activity of novel arylimidamides against Trypanosoma cruzi.
De Araújo JS, Da Silva CF, Batista DG, Da Silva PB, Meuser MB, Aiub CA, da Silva MF, Araújo-Lima CF, Banerjee M, Farahat AA, Stephens CE, Kumar A, Boykin DW, Soeiro MN. De Araújo JS, et al. Among authors: soeiro mn. Antimicrob Agents Chemother. 2014 Jul;58(7):4191-5. doi: 10.1128/AAC.01403-13. Epub 2014 Mar 3. Antimicrob Agents Chemother. 2014. PMID: 24590476 Free PMC article.
Cellular effects of reversed amidines on Trypanosoma cruzi.
Silva CF, Meuser MB, De Souza EM, Meirelles MN, Stephens CE, Som P, Boykin DW, Soeiro MN. Silva CF, et al. Among authors: soeiro mn. Antimicrob Agents Chemother. 2007 Nov;51(11):3803-9. doi: 10.1128/AAC.00047-07. Epub 2007 Aug 13. Antimicrob Agents Chemother. 2007. PMID: 17698624 Free PMC article.
The trypanocidal activity of amidine compounds does not correlate with their binding affinity to Trypanosoma cruzi kinetoplast DNA.
Daliry A, Pires MQ, Silva CF, Pacheco RS, Munde M, Stephens CE, Kumar A, Ismail MA, Liu Z, Farahat AA, Akay S, Som P, Hu Q, Boykin DW, Wilson WD, De Castro SL, Soeiro MN. Daliry A, et al. Among authors: soeiro mn. Antimicrob Agents Chemother. 2011 Oct;55(10):4765-73. doi: 10.1128/AAC.00229-11. Epub 2011 Aug 1. Antimicrob Agents Chemother. 2011. PMID: 21807972 Free PMC article.
In Vitro and In Vivo Trypanosomicidal Action of Novel Arylimidamides against Trypanosoma cruzi.
Guedes-da-Silva FH, Batista DG, Meuser MB, Demarque KC, Fulco TO, Araújo JS, Da Silva PB, Da Silva CF, Patrick DA, Bakunova SM, Bakunov SA, Tidwell RR, Oliveira GM, Britto C, Moreira OC, Soeiro MN. Guedes-da-Silva FH, et al. Among authors: soeiro mn. Antimicrob Agents Chemother. 2016 Mar 25;60(4):2425-34. doi: 10.1128/AAC.01667-15. Print 2016 Apr. Antimicrob Agents Chemother. 2016. PMID: 26856830 Free PMC article.
Phenotypic Screening In Vitro of Novel Aromatic Amidines against Trypanosoma cruzi.
Simões-Silva MR, Nefertiti AS, De Araújo JS, Batista MM, Da Silva PB, Bahia MT, Menna-Barreto RS, Pavão BP, Green J, Farahat AA, Kumar A, Boykin DW, Soeiro MN. Simões-Silva MR, et al. Among authors: soeiro mn. Antimicrob Agents Chemother. 2016 Jul 22;60(8):4701-7. doi: 10.1128/AAC.01788-15. Print 2016 Aug. Antimicrob Agents Chemother. 2016. PMID: 27216059 Free PMC article.
Antitrypanosomal Activity of Sterol 14α-Demethylase (CYP51) Inhibitors VNI and VFV in the Swiss Mouse Models of Chagas Disease Induced by the Trypanosoma cruzi Y Strain.
Guedes-da-Silva FH, Batista DG, Da Silva CF, De Araújo JS, Pavão BP, Simões-Silva MR, Batista MM, Demarque KC, Moreira OC, Britto C, Lepesheva GI, Soeiro MN. Guedes-da-Silva FH, et al. Among authors: soeiro mn. Antimicrob Agents Chemother. 2017 Mar 24;61(4):e02098-16. doi: 10.1128/AAC.02098-16. Print 2017 Apr. Antimicrob Agents Chemother. 2017. PMID: 28167559 Free PMC article.
Drug repurposing strategy against Trypanosoma cruzi infection: In vitro and in vivo assessment of the activity of metronidazole in mono- and combined therapy.
Simões-Silva MR, De Araújo JS, Oliveira GM, Demarque KC, Peres RB, D'Almeida-Melo I, Batista DGJ, Da Silva CF, Cardoso-Santos C, Da Silva PB, Batista MM, Bahia MT, Soeiro MNC. Simões-Silva MR, et al. Biochem Pharmacol. 2017 Dec 1;145:46-53. doi: 10.1016/j.bcp.2017.08.025. Epub 2017 Sep 7. Biochem Pharmacol. 2017. PMID: 28870526
70 results