Wiemer AJ - Search Results

1

Cyclopropene cycloadditions with annulated furans: total synthesis of (+)- and (-)-frondosin B and (+)-frondosin A.

Oblak EZ, VanHeyst MD, Li J, Wiemer AJ, Wright DL. Oblak EZ, et al. Among authors: wiemer aj. J Am Chem Soc. 2014 Mar 19;136(11):4309-15. doi: 10.1021/ja413106t. Epub 2014 Mar 10. J Am Chem Soc. 2014. PMID: 24575795

2

Synthesis of a phosphoantigen prodrug that potently activates Vγ9Vδ2 T-lymphocytes.

Hsiao CH, Lin X, Barney RJ, Shippy RR, Li J, Vinogradova O, Wiemer DF, Wiemer AJ. Hsiao CH, et al. Among authors: wiemer aj, wiemer df. Chem Biol. 2014 Aug 14;21(8):945-54. doi: 10.1016/j.chembiol.2014.06.006. Epub 2014 Jul 24. Chem Biol. 2014. PMID: 25065532

3

Evaluation of a 7-Methoxycoumarin-3-carboxylic Acid Ester Derivative as a Fluorescent, Cell-Cleavable, Phosphonate Protecting Group.

Wiemer AJ, Shippy RR, Kilcollins AM, Li J, Hsiao CH, Barney RJ, Geng ML, Wiemer DF. Wiemer AJ, et al. Among authors: wiemer df. Chembiochem. 2016 Jan 1;17(1):52-5. doi: 10.1002/cbic.201500484. Epub 2015 Nov 19. Chembiochem. 2016. PMID: 26503489 Free PMC article.

4

HMBPP Analog Prodrugs Bypass Energy-Dependent Uptake To Promote Efficient BTN3A1-Mediated Malignant Cell Lysis by Vγ9Vδ2 T Lymphocyte Effectors.

Kilcollins AM, Li J, Hsiao CH, Wiemer AJ. Kilcollins AM, et al. Among authors: wiemer aj. J Immunol. 2016 Jul 15;197(2):419-28. doi: 10.4049/jimmunol.1501833. Epub 2016 Jun 6. J Immunol. 2016. PMID: 27271567 Free PMC article.

5

Synthesis and biological evaluation of santacruzamate A analogues for anti-proliferative and immunomodulatory activity.

Gromek SM, deMayo JA, Maxwell AT, West AM, Pavlik CM, Zhao Z, Li J, Wiemer AJ, Zweifach A, Balunas MJ. Gromek SM, et al. Among authors: wiemer aj. Bioorg Med Chem. 2016 Nov 1;24(21):5183-5196. doi: 10.1016/j.bmc.2016.08.040. Epub 2016 Aug 24. Bioorg Med Chem. 2016. PMID: 27614919 Free PMC article.

6

Novel α-substituted tropolones promote potent and selective caspase-dependent leukemia cell apoptosis.

Li J, Falcone ER, Holstein SA, Anderson AC, Wright DL, Wiemer AJ. Li J, et al. Among authors: wiemer aj. Pharmacol Res. 2016 Nov;113(Pt A):438-448. doi: 10.1016/j.phrs.2016.09.020. Epub 2016 Sep 20. Pharmacol Res. 2016. PMID: 27663262 Free PMC article.

7

Phosphinophosphonates and Their Tris-pivaloyloxymethyl Prodrugs Reveal a Negatively Cooperative Butyrophilin Activation Mechanism.

Shippy RR, Lin X, Agabiti SS, Li J, Zangari BM, Foust BJ, Poe MM, Hsiao CC, Vinogradova O, Wiemer DF, Wiemer AJ. Shippy RR, et al. Among authors: wiemer aj, wiemer df. J Med Chem. 2017 Mar 23;60(6):2373-2382. doi: 10.1021/acs.jmedchem.6b00965. Epub 2017 Mar 1. J Med Chem. 2017. PMID: 28218845 Free PMC article.

8

Geranylgeranyl diphosphate synthase inhibition induces apoptosis that is dependent upon GGPP depletion, ERK phosphorylation and caspase activation.

Agabiti SS, Li J, Wiemer AJ. Agabiti SS, et al. Among authors: wiemer aj. Cell Death Dis. 2017 Mar 16;8(3):e2678. doi: 10.1038/cddis.2017.101. Cell Death Dis. 2017. PMID: 28300835 Free PMC article.

9

The butyrophilin 3A1 intracellular domain undergoes a conformational change involving the juxtamembrane region.

Nguyen K, Li J, Puthenveetil R, Lin X, Poe MM, Hsiao CC, Vinogradova O, Wiemer AJ. Nguyen K, et al. Among authors: wiemer aj. FASEB J. 2017 Nov;31(11):4697-4706. doi: 10.1096/fj.201601370RR. Epub 2017 Jul 13. FASEB J. 2017. PMID: 28705810 Free PMC article.

10

Novel tropolones induce the unfolded protein response pathway and apoptosis in multiple myeloma cells.

Haney SL, Allen C, Varney ML, Dykstra KM, Falcone ER, Colligan SH, Hu Q, Aldridge AM, Wright DL, Wiemer AJ, Holstein SA. Haney SL, et al. Among authors: wiemer aj. Oncotarget. 2017 Jun 16;8(44):76085-76098. doi: 10.18632/oncotarget.18543. eCollection 2017 Sep 29. Oncotarget. 2017. PMID: 29100294 Free PMC article.

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