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The benzenesulfoamide T0901317 [N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide] is a novel retinoic acid receptor-related orphan receptor-alpha/gamma inverse agonist.
Kumar N, Solt LA, Conkright JJ, Wang Y, Istrate MA, Busby SA, Garcia-Ordonez RD, Burris TP, Griffin PR. Kumar N, et al. Among authors: griffin pr. Mol Pharmacol. 2010 Feb;77(2):228-36. doi: 10.1124/mol.109.060905. Epub 2009 Nov 3. Mol Pharmacol. 2010. PMID: 19887649 Free PMC article.
Regulation of adipogenesis by natural and synthetic REV-ERB ligands.
Kumar N, Solt LA, Wang Y, Rogers PM, Bhattacharyya G, Kamenecka TM, Stayrook KR, Crumbley C, Floyd ZE, Gimble JM, Griffin PR, Burris TP. Kumar N, et al. Among authors: griffin pr. Endocrinology. 2010 Jul;151(7):3015-25. doi: 10.1210/en.2009-0800. Epub 2010 Apr 28. Endocrinology. 2010. PMID: 20427485 Free PMC article.
Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5.
Choi JH, Banks AS, Estall JL, Kajimura S, Boström P, Laznik D, Ruas JL, Chalmers MJ, Kamenecka TM, Blüher M, Griffin PR, Spiegelman BM. Choi JH, et al. Among authors: griffin pr. Nature. 2010 Jul 22;466(7305):451-6. doi: 10.1038/nature09291. Nature. 2010. PMID: 20651683 Free PMC article.
Identification of SR3335 (ML-176): a synthetic RORα selective inverse agonist.
Kumar N, Kojetin DJ, Solt LA, Kumar KG, Nuhant P, Duckett DR, Cameron MD, Butler AA, Roush WR, Griffin PR, Burris TP. Kumar N, et al. Among authors: griffin pr. ACS Chem Biol. 2011 Mar 18;6(3):218-22. doi: 10.1021/cb1002762. Epub 2010 Dec 6. ACS Chem Biol. 2011. PMID: 21090593 Free PMC article.
284 results