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Page 1
Targeting RPL39 and MLF2 reduces tumor initiation and metastasis in breast cancer by inhibiting nitric oxide synthase signaling.
Dave B, Granados-Principal S, Zhu R, Benz S, Rabizadeh S, Soon-Shiong P, Yu KD, Shao Z, Li X, Gilcrease M, Lai Z, Chen Y, Huang TH, Shen H, Liu X, Ferrari M, Zhan M, Wong ST, Kumaraswami M, Mittal V, Chen X, Gross SS, Chang JC. Dave B, et al. Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8838-43. doi: 10.1073/pnas.1320769111. Epub 2014 May 29. Proc Natl Acad Sci U S A. 2014. PMID: 24876273 Free PMC article.
Activating Transcription Factor 4 Modulates TGFβ-Induced Aggressiveness in Triple-Negative Breast Cancer via SMAD2/3/4 and mTORC2 Signaling.
González-González A, Muñoz-Muela E, Marchal JA, Cara FE, Molina MP, Cruz-Lozano M, Jiménez G, Verma A, Ramírez A, Qian W, Chen W, Kozielski AJ, Elemento O, Martín-Salvago MD, Luque RJ, Rosa-Garrido C, Landeira D, Quintana-Romero M, Rosato RR, García MA, Ramirez-Tortosa CL, Kim H, Rodriguez-Aguayo C, Lopez-Berestein G, Sood AK, Lorente JA, Sánchez-Rovira P, Chang JC, Granados-Principal S. González-González A, et al. Clin Cancer Res. 2018 Nov 15;24(22):5697-5709. doi: 10.1158/1078-0432.CCR-17-3125. Epub 2018 Jul 16. Clin Cancer Res. 2018. PMID: 30012564
Hydroxytyrosol inhibits cancer stem cells and the metastatic capacity of triple-negative breast cancer cell lines by the simultaneous targeting of epithelial-to-mesenchymal transition, Wnt/β-catenin and TGFβ signaling pathways.
Cruz-Lozano M, González-González A, Marchal JA, Muñoz-Muela E, Molina MP, Cara FE, Brown AM, García-Rivas G, Hernández-Brenes C, Lorente JA, Sanchez-Rovira P, Chang JC, Granados-Principal S. Cruz-Lozano M, et al. Eur J Nutr. 2019 Dec;58(8):3207-3219. doi: 10.1007/s00394-018-1864-1. Epub 2018 Nov 21. Eur J Nutr. 2019. PMID: 30460610
Antioxidants for the Treatment of Breast Cancer: Are We There Yet?
Griñan-Lison C, Blaya-Cánovas JL, López-Tejada A, Ávalos-Moreno M, Navarro-Ocón A, Cara FE, González-González A, Lorente JA, Marchal JA, Granados-Principal S. Griñan-Lison C, et al. Among authors: granados principal s. Antioxidants (Basel). 2021 Jan 31;10(2):205. doi: 10.3390/antiox10020205. Antioxidants (Basel). 2021. PMID: 33572626 Free PMC article. Review.
GARP is a key molecule for mesenchymal stromal cell responses to TGF-β and fundamental to control mitochondrial ROS levels.
Carrillo-Gálvez AB, Gálvez-Peisl S, González-Correa JE, de Haro-Carrillo M, Ayllón V, Carmona-Sáez P, Ramos-Mejía V, Galindo-Moreno P, Cara FE, Granados-Principal S, Muñoz P, Martin F, Anderson P. Carrillo-Gálvez AB, et al. Among authors: granados principal s. Stem Cells Transl Med. 2020 May;9(5):636-650. doi: 10.1002/sctm.19-0372. Epub 2020 Feb 19. Stem Cells Transl Med. 2020. PMID: 32073751 Free PMC article.
Nanomedicine as a Promising Tool to Overcome Immune Escape in Breast Cancer.
Navarro-Ocón A, Blaya-Cánovas JL, López-Tejada A, Blancas I, Sánchez-Martín RM, Garrido MJ, Griñán-Lisón C, Calahorra J, Cara FE, Ruiz-Cabello F, Marchal JA, Aptsiauri N, Granados-Principal S. Navarro-Ocón A, et al. Among authors: granados principal s. Pharmaceutics. 2022 Feb 25;14(3):505. doi: 10.3390/pharmaceutics14030505. Pharmaceutics. 2022. PMID: 35335881 Free PMC article. Review.
EZH2 endorses cell plasticity to non-small cell lung cancer cells facilitating mesenchymal to epithelial transition and tumour colonization.
Gallardo A, Molina A, Asenjo HG, Lopez-Onieva L, Martorell-Marugán J, Espinosa-Martinez M, Griñan-Lison C, Alvarez-Perez JC, Cara FE, Navarro-Marchal SA, Carmona-Sáez P, Medina PP, Marchal JA, Granados-Principal S, Sánchez-Pozo A, Landeira D. Gallardo A, et al. Among authors: granados principal s. Oncogene. 2022 Jul;41(28):3611-3624. doi: 10.1038/s41388-022-02375-x. Epub 2022 Jun 9. Oncogene. 2022. PMID: 35680984
TGFβ Governs the Pleiotropic Activity of NDRG1 in Triple-Negative Breast Cancer Progression.
López-Tejada A, Griñán-Lisón C, González-González A, Cara FE, Luque RJ, Rosa-Garrido C, Blaya-Cánovas JL, Navarro-Ocón A, Valenzuela-Torres M, Parra-López M, Calahorra J, Blancas I, Marchal JA, Granados-Principal S. López-Tejada A, et al. Among authors: granados principal s. Int J Biol Sci. 2023 Jan 1;19(1):204-224. doi: 10.7150/ijbs.78738. eCollection 2023. Int J Biol Sci. 2023. PMID: 36594086 Free PMC article.
38 results