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Page 1
Colocalized delivery of rapamycin and paclitaxel to tumors enhances synergistic targeting of the PI3K/Akt/mTOR pathway.
Blanco E, Sangai T, Wu S, Hsiao A, Ruiz-Esparza GU, Gonzalez-Delgado CA, Cara FE, Granados-Principal S, Evans KW, Akcakanat A, Wang Y, Do KA, Meric-Bernstam F, Ferrari M. Blanco E, et al. Among authors: cara fe. Mol Ther. 2014 Jul;22(7):1310-1319. doi: 10.1038/mt.2014.27. Epub 2014 Feb 26. Mol Ther. 2014. PMID: 24569835 Free PMC article.
A specifically designed nanoconstruct associates, internalizes, traffics in cardiovascular cells, and accumulates in failing myocardium: a new strategy for heart failure diagnostics and therapeutics.
Ruiz-Esparza GU, Segura-Ibarra V, Cordero-Reyes AM, Youker KA, Serda RE, Cruz-Solbes AS, Amione-Guerra J, Yokoi K, Kirui DK, Cara FE, Paez-Mayorga J, Flores-Arredondo JH, Guerrero-Beltrán CE, Garcia-Rivas G, Ferrari M, Blanco E, Torre-Amione G. Ruiz-Esparza GU, et al. Among authors: cara fe. Eur J Heart Fail. 2016 Feb;18(2):169-78. doi: 10.1002/ejhf.463. Epub 2016 Jan 7. Eur J Heart Fail. 2016. PMID: 26749465 Free PMC article.
Rapamycin nanoparticles localize in diseased lung vasculature and prevent pulmonary arterial hypertension.
Segura-Ibarra V, Amione-Guerra J, Cruz-Solbes AS, Cara FE, Iruegas-Nunez DA, Wu S, Youker KA, Bhimaraj A, Torre-Amione G, Ferrari M, Karmouty-Quintana H, Guha A, Blanco E. Segura-Ibarra V, et al. Among authors: cara fe. Int J Pharm. 2017 May 30;524(1-2):257-267. doi: 10.1016/j.ijpharm.2017.03.069. Epub 2017 Mar 28. Int J Pharm. 2017. PMID: 28359821
Activating Transcription Factor 4 Modulates TGFβ-Induced Aggressiveness in Triple-Negative Breast Cancer via SMAD2/3/4 and mTORC2 Signaling.
González-González A, Muñoz-Muela E, Marchal JA, Cara FE, Molina MP, Cruz-Lozano M, Jiménez G, Verma A, Ramírez A, Qian W, Chen W, Kozielski AJ, Elemento O, Martín-Salvago MD, Luque RJ, Rosa-Garrido C, Landeira D, Quintana-Romero M, Rosato RR, García MA, Ramirez-Tortosa CL, Kim H, Rodriguez-Aguayo C, Lopez-Berestein G, Sood AK, Lorente JA, Sánchez-Rovira P, Chang JC, Granados-Principal S. González-González A, et al. Among authors: cara fe. Clin Cancer Res. 2018 Nov 15;24(22):5697-5709. doi: 10.1158/1078-0432.CCR-17-3125. Epub 2018 Jul 16. Clin Cancer Res. 2018. PMID: 30012564
Hydroxytyrosol inhibits cancer stem cells and the metastatic capacity of triple-negative breast cancer cell lines by the simultaneous targeting of epithelial-to-mesenchymal transition, Wnt/β-catenin and TGFβ signaling pathways.
Cruz-Lozano M, González-González A, Marchal JA, Muñoz-Muela E, Molina MP, Cara FE, Brown AM, García-Rivas G, Hernández-Brenes C, Lorente JA, Sanchez-Rovira P, Chang JC, Granados-Principal S. Cruz-Lozano M, et al. Among authors: cara fe. Eur J Nutr. 2019 Dec;58(8):3207-3219. doi: 10.1007/s00394-018-1864-1. Epub 2018 Nov 21. Eur J Nutr. 2019. PMID: 30460610
Antioxidants for the Treatment of Breast Cancer: Are We There Yet?
Griñan-Lison C, Blaya-Cánovas JL, López-Tejada A, Ávalos-Moreno M, Navarro-Ocón A, Cara FE, González-González A, Lorente JA, Marchal JA, Granados-Principal S. Griñan-Lison C, et al. Among authors: cara fe. Antioxidants (Basel). 2021 Jan 31;10(2):205. doi: 10.3390/antiox10020205. Antioxidants (Basel). 2021. PMID: 33572626 Free PMC article. Review.
Nanomedicine as a Promising Tool to Overcome Immune Escape in Breast Cancer.
Navarro-Ocón A, Blaya-Cánovas JL, López-Tejada A, Blancas I, Sánchez-Martín RM, Garrido MJ, Griñán-Lisón C, Calahorra J, Cara FE, Ruiz-Cabello F, Marchal JA, Aptsiauri N, Granados-Principal S. Navarro-Ocón A, et al. Among authors: cara fe. Pharmaceutics. 2022 Feb 25;14(3):505. doi: 10.3390/pharmaceutics14030505. Pharmaceutics. 2022. PMID: 35335881 Free PMC article. Review.
EZH2 endorses cell plasticity to non-small cell lung cancer cells facilitating mesenchymal to epithelial transition and tumour colonization.
Gallardo A, Molina A, Asenjo HG, Lopez-Onieva L, Martorell-Marugán J, Espinosa-Martinez M, Griñan-Lison C, Alvarez-Perez JC, Cara FE, Navarro-Marchal SA, Carmona-Sáez P, Medina PP, Marchal JA, Granados-Principal S, Sánchez-Pozo A, Landeira D. Gallardo A, et al. Among authors: cara fe. Oncogene. 2022 Jul;41(28):3611-3624. doi: 10.1038/s41388-022-02375-x. Epub 2022 Jun 9. Oncogene. 2022. PMID: 35680984
15 results