Koehn J - Search Results

1

Novel liquid chromatography-tandem mass spectrometry method for simultaneous detection of anti-HIV drugs Lopinavir, Ritonavir, and Tenofovir in plasma.

Koehn J, Ho RJ. Koehn J, et al. Antimicrob Agents Chemother. 2014 May;58(5):2675-80. doi: 10.1128/AAC.02748-13. Epub 2014 Feb 24. Antimicrob Agents Chemother. 2014. PMID: 24566184 Free PMC article.

2

Evaluation of atazanavir and darunavir interactions with lipids for developing pH-responsive anti-HIV drug combination nanoparticles.

Duan J, Freeling JP, Koehn J, Shu C, Ho RJ. Duan J, et al. Among authors: koehn j. J Pharm Sci. 2014 Aug;103(8):2520-9. doi: 10.1002/jps.24046. Epub 2014 Jun 19. J Pharm Sci. 2014. PMID: 24948204 Free PMC article.

3

Long-acting three-drug combination anti-HIV nanoparticles enhance drug exposure in primate plasma and cells within lymph nodes and blood.

Freeling JP, Koehn J, Shu C, Sun J, Ho RJ. Freeling JP, et al. Among authors: koehn j. AIDS. 2014 Nov 13;28(17):2625-7. doi: 10.1097/QAD.0000000000000421. AIDS. 2014. PMID: 25102089 Free PMC article.

4

Anti-HIV drug-combination nanoparticles enhance plasma drug exposure duration as well as triple-drug combination levels in cells within lymph nodes and blood in primates.

Freeling JP, Koehn J, Shu C, Sun J, Ho RJ. Freeling JP, et al. Among authors: koehn j. AIDS Res Hum Retroviruses. 2015 Jan;31(1):107-14. doi: 10.1089/aid.2014.0210. AIDS Res Hum Retroviruses. 2015. PMID: 25402233 Free PMC article.

5

A simple, efficient, and sensitive method for simultaneous detection of anti-HIV drugs atazanavir, ritonavir, and tenofovir by use of liquid chromatography-tandem mass spectrometry.

Koehn J, Ding Y, Freeling J, Duan J, Ho RJ. Koehn J, et al. Antimicrob Agents Chemother. 2015 Nov;59(11):6682-8. doi: 10.1128/AAC.00869-15. Epub 2015 Jul 27. Antimicrob Agents Chemother. 2015. PMID: 26248367 Free PMC article.

6

Long-acting combination anti-HIV drug suspension enhances and sustains higher drug levels in lymph node cells than in blood cells and plasma.

Kraft JC, McConnachie LA, Koehn J, Kinman L, Collins C, Shen DD, Collier AC, Ho RJ. Kraft JC, et al. Among authors: koehn j. AIDS. 2017 Mar 27;31(6):765-770. doi: 10.1097/QAD.0000000000001405. AIDS. 2017. PMID: 28099191 Free PMC article.

7

Mechanism-based pharmacokinetic (MBPK) models describe the complex plasma kinetics of three antiretrovirals delivered by a long-acting anti-HIV drug combination nanoparticle formulation.

Kraft JC, McConnachie LA, Koehn J, Kinman L, Sun J, Collier AC, Collins C, Shen DD, Ho RJY. Kraft JC, et al. Among authors: koehn j. J Control Release. 2018 Apr 10;275:229-241. doi: 10.1016/j.jconrel.2018.02.003. Epub 2018 Feb 10. J Control Release. 2018. PMID: 29432823 Free PMC article.

8

Long-Acting Profile of 4 Drugs in 1 Anti-HIV Nanosuspension in Nonhuman Primates for 5 Weeks After a Single Subcutaneous Injection.

McConnachie LA, Kinman LM, Koehn J, Kraft JC, Lane S, Lee W, Collier AC, Ho RJY. McConnachie LA, et al. Among authors: koehn j. J Pharm Sci. 2018 Jul;107(7):1787-1790. doi: 10.1016/j.xphs.2018.03.005. Epub 2018 Mar 13. J Pharm Sci. 2018. PMID: 29548975 Free PMC article.

9

Extended cell and plasma drug levels after one dose of a three-in-one nanosuspension containing lopinavir, efavirenz, and tenofovir in nonhuman primates.

Koehn J, Iwamoto JF, Kraft JC, McConnachie LA, Collier AC, Ho RJY. Koehn J, et al. AIDS. 2018 Nov 13;32(17):2463-2467. doi: 10.1097/QAD.0000000000001969. AIDS. 2018. PMID: 30102655 Free PMC article.

10

Three HIV Drugs, Atazanavir, Ritonavir, and Tenofovir, Coformulated in Drug-Combination Nanoparticles Exhibit Long-Acting and Lymphocyte-Targeting Properties in Nonhuman Primates.

Perazzolo S, Shireman LM, Koehn J, McConnachie LA, Kraft JC, Shen DD, Ho RJY. Perazzolo S, et al. Among authors: koehn j. J Pharm Sci. 2018 Dec;107(12):3153-3162. doi: 10.1016/j.xphs.2018.07.032. Epub 2018 Aug 16. J Pharm Sci. 2018. PMID: 30121315 Free PMC article.

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