Eckhardt LL - Search Results

1

KCNJ2 mutation causes an adrenergic-dependent rectification abnormality with calcium sensitivity and ventricular arrhythmia.

Kalscheur MM, Vaidyanathan R, Orland KM, Abozeid S, Fabry N, Maginot KR, January CT, Makielski JC, Eckhardt LL. Kalscheur MM, et al. Among authors: eckhardt ll. Heart Rhythm. 2014 May;11(5):885-94. doi: 10.1016/j.hrthm.2014.02.015. Epub 2014 Feb 21. Heart Rhythm. 2014. PMID: 24561538 Free PMC article.

2

Protein trafficking abnormalities: a new mechanism in drug-induced long QT syndrome.

Eckhardt LL, Rajamani S, January CT. Eckhardt LL, et al. Br J Pharmacol. 2005 May;145(1):3-4. doi: 10.1038/sj.bjp.0706143. Br J Pharmacol. 2005. PMID: 15711590 Free PMC article.

3

Specific serine proteases selectively damage KCNH2 (hERG1) potassium channels and I(Kr).

Rajamani S, Anderson CL, Valdivia CR, Eckhardt LL, Foell JD, Robertson GA, Kamp TJ, Makielski JC, Anson BD, January CT. Rajamani S, et al. Among authors: eckhardt ll. Am J Physiol Heart Circ Physiol. 2006 Mar;290(3):H1278-88. doi: 10.1152/ajpheart.00777.2005. Epub 2005 Oct 14. Am J Physiol Heart Circ Physiol. 2006. PMID: 16227340 Free article.

4

Drug-induced long QT syndrome: hERG K+ channel block and disruption of protein trafficking by fluoxetine and norfluoxetine.

Rajamani S, Eckhardt LL, Valdivia CR, Klemens CA, Gillman BM, Anderson CL, Holzem KM, Delisle BP, Anson BD, Makielski JC, January CT. Rajamani S, et al. Among authors: eckhardt ll. Br J Pharmacol. 2006 Nov;149(5):481-9. doi: 10.1038/sj.bjp.0706892. Epub 2006 Sep 11. Br J Pharmacol. 2006. PMID: 16967046 Free PMC article.

5

KCNJ2 mutations in arrhythmia patients referred for LQT testing: a mutation T305A with novel effect on rectification properties.

Eckhardt LL, Farley AL, Rodriguez E, Ruwaldt K, Hammill D, Tester DJ, Ackerman MJ, Makielski JC. Eckhardt LL, et al. Heart Rhythm. 2007 Mar;4(3):323-9. doi: 10.1016/j.hrthm.2006.10.025. Epub 2006 Nov 10. Heart Rhythm. 2007. PMID: 17341397 Free PMC article.

6

Is ranolazine an antiarrhythmic drug?

Eckhardt LL, Teelin TC, January CT. Eckhardt LL, et al. Am J Physiol Heart Circ Physiol. 2008 May;294(5):H1989-91. doi: 10.1152/ajpheart.00285.2008. Epub 2008 Mar 28. Am J Physiol Heart Circ Physiol. 2008. PMID: 18375723 Free article. No abstract available.

7

Gain-of-function mutation S422L in the KCNJ8-encoded cardiac K(ATP) channel Kir6.1 as a pathogenic substrate for J-wave syndromes.

Medeiros-Domingo A, Tan BH, Crotti L, Tester DJ, Eckhardt L, Cuoretti A, Kroboth SL, Song C, Zhou Q, Kopp D, Schwartz PJ, Makielski JC, Ackerman MJ. Medeiros-Domingo A, et al. Heart Rhythm. 2010 Oct;7(10):1466-71. doi: 10.1016/j.hrthm.2010.06.016. Epub 2010 Jun 15. Heart Rhythm. 2010. PMID: 20558321 Free PMC article.

8

The interaction of caveolin 3 protein with the potassium inward rectifier channel Kir2.1: physiology and pathology related to long qt syndrome 9 (LQT9).

Vaidyanathan R, Vega AL, Song C, Zhou Q, Tan BH, Berger S, Makielski JC, Eckhardt LL. Vaidyanathan R, et al. Among authors: eckhardt ll. J Biol Chem. 2013 Jun 14;288(24):17472-80. doi: 10.1074/jbc.M112.435370. Epub 2013 May 2. J Biol Chem. 2013. PMID: 23640888 Free PMC article.

9

hERG 1b is critical for human cardiac repolarization.

Jones DK, Liu F, Vaidyanathan R, Eckhardt LL, Trudeau MC, Robertson GA. Jones DK, et al. Among authors: eckhardt ll. Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):18073-7. doi: 10.1073/pnas.1414945111. Epub 2014 Dec 1. Proc Natl Acad Sci U S A. 2014. PMID: 25453103 Free PMC article.

10

Monomorphic ventricular tachycardia in Brugada syndrome: True-true but related?

Eckhardt LL. Eckhardt LL. Heart Rhythm. 2016 Mar;13(3):683-5. doi: 10.1016/j.hrthm.2015.11.039. Epub 2015 Nov 26. Heart Rhythm. 2016. PMID: 26632641 Free PMC article. No abstract available.

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