Guo H - Search Results

1

Proinsulin entry and transit through the endoplasmic reticulum in pancreatic beta cells.

Liu M, Wright J, Guo H, Xiong Y, Arvan P. Liu M, et al. Among authors: guo h. Vitam Horm. 2014;95:35-62. doi: 10.1016/B978-0-12-800174-5.00002-8. Vitam Horm. 2014. PMID: 24559913 Review.

2

Impaired cleavage of preproinsulin signal peptide linked to autosomal-dominant diabetes.

Liu M, Lara-Lemus R, Shan SO, Wright J, Haataja L, Barbetti F, Guo H, Larkin D, Arvan P. Liu M, et al. Among authors: guo h. Diabetes. 2012 Apr;61(4):828-37. doi: 10.2337/db11-0878. Epub 2012 Feb 22. Diabetes. 2012. PMID: 22357960 Free PMC article.

3

Inefficient translocation of preproinsulin contributes to pancreatic β cell failure and late-onset diabetes.

Guo H, Xiong Y, Witkowski P, Cui J, Wang LJ, Sun J, Lara-Lemus R, Haataja L, Hutchison K, Shan SO, Arvan P, Liu M. Guo H, et al. J Biol Chem. 2014 Jun 6;289(23):16290-302. doi: 10.1074/jbc.M114.562355. Epub 2014 Apr 25. J Biol Chem. 2014. PMID: 24770419 Free PMC article.

4

INS-gene mutations: from genetics and beta cell biology to clinical disease.

Liu M, Sun J, Cui J, Chen W, Guo H, Barbetti F, Arvan P. Liu M, et al. Among authors: guo h. Mol Aspects Med. 2015 Apr;42:3-18. doi: 10.1016/j.mam.2014.12.001. Epub 2014 Dec 24. Mol Aspects Med. 2015. PMID: 25542748 Free PMC article. Review.

5

Competitive Inhibition of the Endoplasmic Reticulum Signal Peptidase by Non-cleavable Mutant Preprotein Cargos.

Cui J, Chen W, Sun J, Guo H, Madley R, Xiong Y, Pan X, Wang H, Tai AW, Weiss MA, Arvan P, Liu M. Cui J, et al. Among authors: guo h. J Biol Chem. 2015 Nov 20;290(47):28131-28140. doi: 10.1074/jbc.M115.692350. Epub 2015 Oct 7. J Biol Chem. 2015. PMID: 26446786 Free PMC article.

6

Positive charge in the n-region of the signal peptide contributes to efficient post-translational translocation of small secretory preproteins.

Guo H, Sun J, Li X, Xiong Y, Wang H, Shu H, Zhu R, Liu Q, Huang Y, Madley R, Wang Y, Cui J, Arvan P, Liu M. Guo H, et al. J Biol Chem. 2018 Feb 9;293(6):1899-1907. doi: 10.1074/jbc.RA117.000922. Epub 2017 Dec 11. J Biol Chem. 2018. PMID: 29229776 Free PMC article.

7

"Register-shift" insulin analogs uncover constraints of proteotoxicity in protein evolution.

Rege NK, Liu M, Dhayalan B, Chen YS, Smith NA, Rahimi L, Sun J, Guo H, Yang Y, Haataja L, Phillips NFB, Whittaker J, Smith BJ, Arvan P, Ismail-Beigi F, Weiss MA. Rege NK, et al. Among authors: guo h. J Biol Chem. 2020 Mar 6;295(10):3080-3098. doi: 10.1074/jbc.RA119.011389. Epub 2020 Jan 31. J Biol Chem. 2020. PMID: 32005662 Free PMC article.

8

Evolution of insulin at the edge of foldability and its medical implications.

Rege NK, Liu M, Yang Y, Dhayalan B, Wickramasinghe NP, Chen YS, Rahimi L, Guo H, Haataja L, Sun J, Ismail-Beigi F, Phillips NB, Arvan P, Weiss MA. Rege NK, et al. Among authors: guo h. Proc Natl Acad Sci U S A. 2020 Nov 24;117(47):29618-29628. doi: 10.1073/pnas.2010908117. Epub 2020 Nov 5. Proc Natl Acad Sci U S A. 2020. PMID: 33154160 Free PMC article.

9

The integrated teaching practice of medical cloud dictionary development and project-based learning.

Zhang J, Chen J, Guo H, Liu W, Li M. Zhang J, et al. Among authors: guo h. BMC Med Educ. 2025 Jan 8;25(1):30. doi: 10.1186/s12909-024-06621-6. BMC Med Educ. 2025. PMID: 39780120

10

Evaluation of heavy metal accumulation and sources in surface sediments of the Pearl River Estuary (China).

Liang H, Wang G, Guo H, Niu L, Yang Q. Liang H, et al. Among authors: guo h. Mar Environ Res. 2025 Jan 3;204:106948. doi: 10.1016/j.marenvres.2025.106948. Online ahead of print. Mar Environ Res. 2025. PMID: 39778254

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