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ALS-associated C21ORF2 variant disrupts DNA damage repair, mitochondrial metabolism, neuronal excitability and NEK1 levels in human motor neurons.
Zelina P, de Ruiter AA, Kolsteeg C, van Ginneken I, Vos HR, Supiot LF, Burgering BMT, Meye FJ, Veldink JH, van den Berg LH, Pasterkamp RJ. Zelina P, et al. Among authors: burgering bmt. Acta Neuropathol Commun. 2024 Sep 4;12(1):144. doi: 10.1186/s40478-024-01852-6. Acta Neuropathol Commun. 2024. PMID: 39227882 Free PMC article.
Mitochondrial H2O2 release does not directly cause damage to chromosomal DNA.
van Soest DMK, Polderman PE, den Toom WTF, Keijer JP, van Roosmalen MJ, Leyten TMF, Lehmann J, Zwakenberg S, De Henau S, van Boxtel R, Burgering BMT, Dansen TB. van Soest DMK, et al. Among authors: burgering bmt. Nat Commun. 2024 Mar 28;15(1):2725. doi: 10.1038/s41467-024-47008-x. Nat Commun. 2024. PMID: 38548751 Free PMC article.
Targeted perturbation of signaling-driven condensates.
Gui T, Fleming C, Manzato C, Bourgeois B, Sirati N, Heuer J, Papadionysiou I, Montfort DIV, Gijzen MV, Smits LMM, Burgering BMT, Madl T, Schuijers J. Gui T, et al. Among authors: burgering bmt. Mol Cell. 2023 Nov 16;83(22):4141-4157.e11. doi: 10.1016/j.molcel.2023.10.023. Epub 2023 Nov 16. Mol Cell. 2023. PMID: 37977121 Free article.
FOXO transcription factors as mediators of stress adaptation.
Rodriguez-Colman MJ, Dansen TB, Burgering BMT. Rodriguez-Colman MJ, et al. Among authors: burgering bmt. Nat Rev Mol Cell Biol. 2024 Jan;25(1):46-64. doi: 10.1038/s41580-023-00649-0. Epub 2023 Sep 14. Nat Rev Mol Cell Biol. 2024. PMID: 37710009 Review.
Pyruvate metabolism controls chromatin remodeling during CD4+ T cell activation.
Mocholi E, Russo L, Gopal K, Ramstead AG, Hochrein SM, Vos HR, Geeven G, Adegoke AO, Hoekstra A, van Es RM, Pittol JR, Vastert S, Rutter J, Radstake T, van Loosdregt J, Berkers C, Mokry M, Anderson CC, O'Connell RM, Vaeth M, Ussher J, Burgering BMT, Coffer PJ. Mocholi E, et al. Among authors: burgering bmt. Cell Rep. 2023 Jun 27;42(6):112583. doi: 10.1016/j.celrep.2023.112583. Epub 2023 Jun 1. Cell Rep. 2023. PMID: 37267106 Free article.
144 results