Ovaa H - Search Results

1

Molecular characterization of ubiquitin-specific protease 18 reveals substrate specificity for interferon-stimulated gene 15.

Basters A, Geurink PP, El Oualid F, Ketscher L, Casutt MS, Krause E, Ovaa H, Knobeloch KP, Fritz G. Basters A, et al. Among authors: ovaa h. FEBS J. 2014 Apr;281(7):1918-28. doi: 10.1111/febs.12754. Epub 2014 Mar 3. FEBS J. 2014. PMID: 24533902 Free article.

2

Nonhydrolyzable ubiquitin-isopeptide isosteres as deubiquitinating enzyme probes.

Shanmugham A, Fish A, Luna-Vargas MP, Faesen AC, El Oualid F, Sixma TK, Ovaa H. Shanmugham A, et al. Among authors: ovaa h. J Am Chem Soc. 2010 Jul 7;132(26):8834-5. doi: 10.1021/ja101803s. J Am Chem Soc. 2010. PMID: 20540574

3

Chemical synthesis of ubiquitin, ubiquitin-based probes, and diubiquitin.

El Oualid F, Merkx R, Ekkebus R, Hameed DS, Smit JJ, de Jong A, Hilkmann H, Sixma TK, Ovaa H. El Oualid F, et al. Among authors: ovaa h. Angew Chem Int Ed Engl. 2010 Dec 27;49(52):10149-53. doi: 10.1002/anie.201005995. Angew Chem Int Ed Engl. 2010. PMID: 21117055 Free PMC article. No abstract available.

4

An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains.

Licchesi JD, Mieszczanek J, Mevissen TE, Rutherford TJ, Akutsu M, Virdee S, El Oualid F, Chin JW, Ovaa H, Bienz M, Komander D. Licchesi JD, et al. Among authors: ovaa h. Nat Struct Mol Biol. 2011 Dec 11;19(1):62-71. doi: 10.1038/nsmb.2169. Nat Struct Mol Biol. 2011. PMID: 22157957 Free PMC article.

5

The differential modulation of USP activity by internal regulatory domains, interactors and eight ubiquitin chain types.

Faesen AC, Luna-Vargas MP, Geurink PP, Clerici M, Merkx R, van Dijk WJ, Hameed DS, El Oualid F, Ovaa H, Sixma TK. Faesen AC, et al. Among authors: ovaa h. Chem Biol. 2011 Dec 23;18(12):1550-61. doi: 10.1016/j.chembiol.2011.10.017. Chem Biol. 2011. PMID: 22195557

6

A general chemical ligation approach towards isopeptide-linked ubiquitin and ubiquitin-like assay reagents.

Geurink PP, El Oualid F, Jonker A, Hameed DS, Ovaa H. Geurink PP, et al. Among authors: ovaa h. Chembiochem. 2012 Jan 23;13(2):293-7. doi: 10.1002/cbic.201100706. Epub 2011 Dec 23. Chembiochem. 2012. PMID: 22213387 Free PMC article. No abstract available.

7

Synthesis and evaluation of a selective fluorogenic Pup derived assay reagent for Dop, a potential drug target in Mycobacterium tuberculosis.

Merkx R, Burns KE, Slobbe P, El Oualid F, El Atmioui D, Darwin KH, Ovaa H. Merkx R, et al. Among authors: ovaa h. Chembiochem. 2012 Sep 24;13(14):2056-60. doi: 10.1002/cbic.201200460. Epub 2012 Aug 24. Chembiochem. 2012. PMID: 22927162 Free PMC article.

8

On terminal alkynes that can react with active-site cysteine nucleophiles in proteases.

Ekkebus R, van Kasteren SI, Kulathu Y, Scholten A, Berlin I, Geurink PP, de Jong A, Goerdayal S, Neefjes J, Heck AJ, Komander D, Ovaa H. Ekkebus R, et al. Among authors: ovaa h. J Am Chem Soc. 2013 Feb 27;135(8):2867-70. doi: 10.1021/ja309802n. Epub 2013 Feb 15. J Am Chem Soc. 2013. PMID: 23387960 Free PMC article.

9

OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis.

Mevissen TE, Hospenthal MK, Geurink PP, Elliott PR, Akutsu M, Arnaudo N, Ekkebus R, Kulathu Y, Wauer T, El Oualid F, Freund SM, Ovaa H, Komander D. Mevissen TE, et al. Among authors: ovaa h. Cell. 2013 Jul 3;154(1):169-84. doi: 10.1016/j.cell.2013.05.046. Cell. 2013. PMID: 23827681 Free PMC article.

10

A native chemical ligation handle that enables the synthesis of advanced activity-based probes: diubiquitin as a case study.

Mulder MP, El Oualid F, ter Beek J, Ovaa H. Mulder MP, et al. Among authors: ovaa h. Chembiochem. 2014 May 5;15(7):946-9. doi: 10.1002/cbic.201402012. Epub 2014 Mar 12. Chembiochem. 2014. PMID: 24623714 Free PMC article.

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