Tainer JA - Search Results

1

The Rad50 hook domain regulates DNA damage signaling and tumorigenesis.

Roset R, Inagaki A, Hohl M, Brenet F, Lafrance-Vanasse J, Lange J, Scandura JM, Tainer JA, Keeney S, Petrini JH. Roset R, et al. Among authors: tainer ja. Genes Dev. 2014 Mar 1;28(5):451-62. doi: 10.1101/gad.236745.113. Epub 2014 Feb 14. Genes Dev. 2014. PMID: 24532689 Free PMC article.

2

The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair.

Hopfner KP, Craig L, Moncalian G, Zinkel RA, Usui T, Owen BA, Karcher A, Henderson B, Bodmer JL, McMurray CT, Carney JP, Petrini JH, Tainer JA. Hopfner KP, et al. Among authors: tainer ja. Nature. 2002 Aug 1;418(6897):562-6. doi: 10.1038/nature00922. Nature. 2002. PMID: 12152085

3

Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.

Williams RS, Williams JS, Tainer JA. Williams RS, et al. Among authors: tainer ja. Biochem Cell Biol. 2007 Aug;85(4):509-20. doi: 10.1139/O07-069. Biochem Cell Biol. 2007. PMID: 17713585 Review.

4

Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair.

Williams RS, Dodson GE, Limbo O, Yamada Y, Williams JS, Guenther G, Classen S, Glover JN, Iwasaki H, Russell P, Tainer JA. Williams RS, et al. Among authors: tainer ja. Cell. 2009 Oct 2;139(1):87-99. doi: 10.1016/j.cell.2009.07.033. Cell. 2009. PMID: 19804755 Free PMC article.

5

Structural dynamics in DNA damage signaling and repair.

Perry JJ, Cotner-Gohara E, Ellenberger T, Tainer JA. Perry JJ, et al. Among authors: tainer ja. Curr Opin Struct Biol. 2010 Jun;20(3):283-94. doi: 10.1016/j.sbi.2010.03.012. Epub 2010 May 1. Curr Opin Struct Biol. 2010. PMID: 20439160 Free PMC article. Review.

6

Mre11-Rad50-Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaks.

Williams GJ, Lees-Miller SP, Tainer JA. Williams GJ, et al. Among authors: tainer ja. DNA Repair (Amst). 2010 Dec 10;9(12):1299-306. doi: 10.1016/j.dnarep.2010.10.001. Epub 2010 Oct 28. DNA Repair (Amst). 2010. PMID: 21035407 Free PMC article. Review.

7

ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling.

Deshpande RA, Williams GJ, Limbo O, Williams RS, Kuhnlein J, Lee JH, Classen S, Guenther G, Russell P, Tainer JA, Paull TT. Deshpande RA, et al. Among authors: tainer ja. EMBO J. 2014 Mar 3;33(5):482-500. doi: 10.1002/embj.201386100. Epub 2014 Feb 3. EMBO J. 2014. PMID: 24493214 Free PMC article.

8

The cutting edges in DNA repair, licensing, and fidelity: DNA and RNA repair nucleases sculpt DNA to measure twice, cut once.

Tsutakawa SE, Lafrance-Vanasse J, Tainer JA. Tsutakawa SE, et al. Among authors: tainer ja. DNA Repair (Amst). 2014 Jul;19:95-107. doi: 10.1016/j.dnarep.2014.03.022. Epub 2014 Apr 19. DNA Repair (Amst). 2014. PMID: 24754999 Free PMC article. Review.

9

Envisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repair.

Lafrance-Vanasse J, Williams GJ, Tainer JA. Lafrance-Vanasse J, et al. Among authors: tainer ja. Prog Biophys Mol Biol. 2015 Mar;117(2-3):182-193. doi: 10.1016/j.pbiomolbio.2014.12.004. Epub 2015 Jan 7. Prog Biophys Mol Biol. 2015. PMID: 25576492 Free PMC article. Review.

10

The MRE11-RAD50-NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair.

Syed A, Tainer JA. Syed A, et al. Among authors: tainer ja. Annu Rev Biochem. 2018 Jun 20;87:263-294. doi: 10.1146/annurev-biochem-062917-012415. Epub 2018 Apr 25. Annu Rev Biochem. 2018. PMID: 29709199 Free PMC article. Review.

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