Lucet I - Search Results

1

An exported kinase (FIKK4.2) that mediates virulence-associated changes in Plasmodium falciparum-infected red blood cells.

Kats LM, Fernandez KM, Glenister FK, Herrmann S, Buckingham DW, Siddiqui G, Sharma L, Bamert R, Lucet I, Guillotte M, Mercereau-Puijalon O, Cooke BM. Kats LM, et al. Among authors: lucet i. Int J Parasitol. 2014 Apr;44(5):319-28. doi: 10.1016/j.ijpara.2014.01.003. Epub 2014 Feb 14. Int J Parasitol. 2014. PMID: 24530877

2

Structure-Guided Prediction of the Functional Impact of DCLK1 Mutations on Tumorigenesis.

Carli ALE, Hardy JM, Hoblos H, Ernst M, Lucet IS, Buchert M. Carli ALE, et al. Among authors: lucet is. Biomedicines. 2023 Mar 22;11(3):990. doi: 10.3390/biomedicines11030990. Biomedicines. 2023. PMID: 36979969 Free PMC article. Review.

3

The structural basis of Janus kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor.

Lucet IS, Fantino E, Styles M, Bamert R, Patel O, Broughton SE, Walter M, Burns CJ, Treutlein H, Wilks AF, Rossjohn J. Lucet IS, et al. Blood. 2006 Jan 1;107(1):176-83. doi: 10.1182/blood-2005-06-2413. Epub 2005 Sep 20. Blood. 2006. PMID: 16174768 Free article.

4

The 2.7 A crystal structure of the autoinhibited human c-Fms kinase domain.

Walter M, Lucet IS, Patel O, Broughton SE, Bamert R, Williams NK, Fantino E, Wilks AF, Rossjohn J. Walter M, et al. J Mol Biol. 2007 Mar 30;367(3):839-47. doi: 10.1016/j.jmb.2007.01.036. Epub 2007 Jan 20. J Mol Biol. 2007. PMID: 17292918

5

Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains.

Williams NK, Bamert RS, Patel O, Wang C, Walden PM, Wilks AF, Fantino E, Rossjohn J, Lucet IS. Williams NK, et al. J Mol Biol. 2009 Mar 20;387(1):219-32. doi: 10.1016/j.jmb.2009.01.041. Epub 2009 Jan 29. J Mol Biol. 2009. PMID: 19361440

6

Plasmodium kinases as targets for new-generation antimalarials.

Lucet IS, Tobin A, Drewry D, Wilks AF, Doerig C. Lucet IS, et al. Future Med Chem. 2012 Dec;4(18):2295-310. doi: 10.4155/fmc.12.183. Future Med Chem. 2012. PMID: 23234552 Review.

7

Production and crystallization of recombinant JAK proteins.

Lucet IS, Bamert R. Lucet IS, et al. Methods Mol Biol. 2013;967:275-300. doi: 10.1007/978-1-62703-242-1_20. Methods Mol Biol. 2013. PMID: 23296737

8

Plasmodium falciparum Adhesins Play an Essential Role in Signalling and Activation of Invasion into Human Erythrocytes.

Tham WH, Lim NT, Weiss GE, Lopaticki S, Ansell BR, Bird M, Lucet I, Dorin-Semblat D, Doerig C, Gilson PR, Crabb BS, Cowman AF. Tham WH, et al. Among authors: lucet i. PLoS Pathog. 2015 Dec 22;11(12):e1005343. doi: 10.1371/journal.ppat.1005343. eCollection 2015 Dec. PLoS Pathog. 2015. PMID: 26694741 Free PMC article.

9

Hierarchical phosphorylation of apical membrane antigen 1 is required for efficient red blood cell invasion by malaria parasites.

Prinz B, Harvey KL, Wilcke L, Ruch U, Engelberg K, Biller L, Lucet I, Erkelenz S, Heincke D, Spielmann T, Doerig C, Kunick C, Crabb BS, Gilson PR, Gilberger TW. Prinz B, et al. Among authors: lucet i. Sci Rep. 2016 Oct 4;6:34479. doi: 10.1038/srep34479. Sci Rep. 2016. PMID: 27698395 Free PMC article.

10

Development and application of a high-throughput screening assay for identification of small molecule inhibitors of the P. falciparum reticulocyte binding-like homologue 5 protein.

Sleebs BE, Jarman KE, Frolich S, Wong W, Healer J, Dai W, Lucet IS, Wilson DW, Cowman AF. Sleebs BE, et al. Int J Parasitol Drugs Drug Resist. 2020 Dec;14:188-200. doi: 10.1016/j.ijpddr.2020.10.008. Epub 2020 Oct 29. Int J Parasitol Drugs Drug Resist. 2020. PMID: 33152623 Free PMC article.

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