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The role of stable α-synuclein oligomers in the molecular events underlying amyloid formation.
Lorenzen N, Nielsen SB, Buell AK, Kaspersen JD, Arosio P, Vad BS, Paslawski W, Christiansen G, Valnickova-Hansen Z, Andreasen M, Enghild JJ, Pedersen JS, Dobson CM, Knowles TP, Otzen DE. Lorenzen N, et al. Among authors: dobson cm. J Am Chem Soc. 2014 Mar 12;136(10):3859-68. doi: 10.1021/ja411577t. Epub 2014 Feb 28. J Am Chem Soc. 2014. PMID: 24527756
Protein aggregation in crowded environments.
White DA, Buell AK, Knowles TP, Welland ME, Dobson CM. White DA, et al. Among authors: dobson cm. J Am Chem Soc. 2010 Apr 14;132(14):5170-5. doi: 10.1021/ja909997e. J Am Chem Soc. 2010. PMID: 20334356
Population of nonnative states of lysozyme variants drives amyloid fibril formation.
Buell AK, Dhulesia A, Mossuto MF, Cremades N, Kumita JR, Dumoulin M, Welland ME, Knowles TPJ, Salvatella X, Dobson CM. Buell AK, et al. Among authors: dobson cm. J Am Chem Soc. 2011 May 25;133(20):7737-7743. doi: 10.1021/ja109620d. Epub 2011 Apr 29. J Am Chem Soc. 2011. PMID: 21528861 Free PMC article.
Role of elongation and secondary pathways in S6 amyloid fibril growth.
Lorenzen N, Cohen SI, Nielsen SB, Herling TW, Christiansen G, Dobson CM, Knowles TP, Otzen D. Lorenzen N, et al. Among authors: dobson cm. Biophys J. 2012 May 2;102(9):2167-75. doi: 10.1016/j.bpj.2012.03.047. Biophys J. 2012. PMID: 22824281 Free PMC article.
The length distribution of frangible biofilaments.
Michaels TC, Yde P, Willis JC, Jensen MH, Otzen D, Dobson CM, Buell AK, Knowles TP. Michaels TC, et al. Among authors: dobson cm. J Chem Phys. 2015 Oct 28;143(16):164901. doi: 10.1063/1.4933230. J Chem Phys. 2015. PMID: 26520548
Metastability of native proteins and the phenomenon of amyloid formation.
Baldwin AJ, Knowles TP, Tartaglia GG, Fitzpatrick AW, Devlin GL, Shammas SL, Waudby CA, Mossuto MF, Meehan S, Gras SL, Christodoulou J, Anthony-Cahill SJ, Barker PD, Vendruscolo M, Dobson CM. Baldwin AJ, et al. Among authors: dobson cm. J Am Chem Soc. 2011 Sep 14;133(36):14160-3. doi: 10.1021/ja2017703. Epub 2011 Aug 19. J Am Chem Soc. 2011. PMID: 21650202
804 results