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An efficient approach to novel 17-5'-(1',2',4')-oxadiazolyl androstenes via the cyclodehydration of cytotoxic O-steroidacylamidoximes, and an evaluation of their inhibitory action on 17α-hydroxylase/C₁₇,₂₀-lyase.
Kovács D, Wölfling J, Szabó N, Szécsi M, Kovács I, Zupkó I, Frank E. Kovács D, et al. Among authors: wolfling j. Eur J Med Chem. 2013;70:649-60. doi: 10.1016/j.ejmech.2013.10.038. Epub 2013 Oct 22. Eur J Med Chem. 2013. PMID: 24211641
Efficient access to novel androsteno-17-(1',3',4')-oxadiazoles and 17β-(1',3',4')-thiadiazoles via N-substituted hydrazone and N,N'-disubstituted hydrazine intermediates, and their pharmacological evaluation in vitro.
Kovács D, Wölfling J, Szabó N, Szécsi M, Minorics R, Zupkó I, Frank É. Kovács D, et al. Among authors: wolfling j. Eur J Med Chem. 2015 Jun 15;98:13-29. doi: 10.1016/j.ejmech.2015.05.010. Epub 2015 May 7. Eur J Med Chem. 2015. PMID: 25993309
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