Werner ER - Search Results

1

Interaction between neuronal nitric-oxide synthase and tetrahydrobiopterin revisited: studies on the nature and mechanism of tight pterin binding.

Heine CL, Kolesnik B, Schmidt R, Werner ER, Mayer B, Gorren AC. Heine CL, et al. Among authors: werner er. Biochemistry. 2014 Mar 4;53(8):1284-95. doi: 10.1021/bi401307r. Epub 2014 Feb 17. Biochemistry. 2014. PMID: 24512289 Free PMC article.

2

Tetrahydrobiopterin protects soluble guanylate cyclase against oxidative inactivation.

Schmidt K, Neubauer A, Kolesnik B, Stasch JP, Werner ER, Gorren AC, Mayer B. Schmidt K, et al. Among authors: werner er. Mol Pharmacol. 2012 Sep;82(3):420-7. doi: 10.1124/mol.112.079855. Epub 2012 May 30. Mol Pharmacol. 2012. PMID: 22648973

3

Cell type-specific recycling of tetrahydrobiopterin by dihydrofolate reductase explains differential effects of 7,8-dihydrobiopterin on endothelial nitric oxide synthase uncoupling.

Schmidt K, Kolesnik B, Gorren AC, Werner ER, Mayer B. Schmidt K, et al. Among authors: werner er. Biochem Pharmacol. 2014 Aug 1;90(3):246-53. doi: 10.1016/j.bcp.2014.05.010. Epub 2014 May 24. Biochem Pharmacol. 2014. PMID: 24863258 Free PMC article.

4

In search of a function for tetrahydrobiopterin in the biosynthesis of nitric oxide.

Mayer B, Werner ER. Mayer B, et al. Among authors: werner er. Naunyn Schmiedebergs Arch Pharmacol. 1995 May;351(5):453-63. doi: 10.1007/BF00171035. Naunyn Schmiedebergs Arch Pharmacol. 1995. PMID: 7543976 Review.

5

Why tetrahydrobiopterin?

Mayer B, Werner ER. Mayer B, et al. Among authors: werner er. Adv Pharmacol. 1995;34:251-61. doi: 10.1016/s1054-3589(08)61090-x. Adv Pharmacol. 1995. PMID: 8562438 Review. No abstract available.

6

Tetrahydrobiopterin-free neuronal nitric oxide synthase: evidence for two identical highly anticooperative pteridine binding sites.

Gorren AC, List BM, Schrammel A, Pitters E, Hemmens B, Werner ER, Schmidt K, Mayer B. Gorren AC, et al. Among authors: werner er. Biochemistry. 1996 Dec 24;35(51):16735-45. doi: 10.1021/bi961931j. Biochemistry. 1996. PMID: 8988010

7

Characterization of bovine endothelial nitric oxide synthase as a homodimer with down-regulated uncoupled NADPH oxidase activity: tetrahydrobiopterin binding kinetics and role of haem in dimerization.

List BM, Klösch B, Völker C, Gorren AC, Sessa WC, Werner ER, Kukovetz WR, Schmidt K, Mayer B. List BM, et al. Among authors: werner er. Biochem J. 1997 Apr 1;323 ( Pt 1)(Pt 1):159-65. doi: 10.1042/bj3230159. Biochem J. 1997. PMID: 9173876 Free PMC article.

8

Tetrahydrobiopterin binding to macrophage inducible nitric oxide synthase: heme spin shift and dimer stabilization by the potent pterin antagonist 4-amino-tetrahydrobiopterin.

Mayer B, Wu C, Gorren AC, Pfeiffer S, Schmidt K, Clark P, Stuehr DJ, Werner ER. Mayer B, et al. Among authors: werner er. Biochemistry. 1997 Jul 8;36(27):8422-7. doi: 10.1021/bi970144z. Biochemistry. 1997. PMID: 9204890

9

Allosteric modulation of rat brain nitric oxide synthase by the pterin-site enzyme inhibitor 4-aminotetrahydrobiopterin.

Pfeiffer S, Gorren AC, Pitters E, Schmidt K, Werner ER, Mayer B. Pfeiffer S, et al. Among authors: werner er. Biochem J. 1997 Dec 1;328 ( Pt 2)(Pt 2):349-52. doi: 10.1042/bj3280349. Biochem J. 1997. PMID: 9371687 Free PMC article.

10

Haem insertion, dimerization and reactivation of haem-free rat neuronal nitric oxide synthase.

Hemmens B, Gorren AC, Schmidt K, Werner ER, Mayer B. Hemmens B, et al. Among authors: werner er. Biochem J. 1998 Jun 1;332 ( Pt 2)(Pt 2):337-42. doi: 10.1042/bj3320337. Biochem J. 1998. PMID: 9601061 Free PMC article.

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