Stephens B - Search Results

1

A general method for site specific fluorescent labeling of recombinant chemokines.

Kawamura T, Stephens B, Qin L, Yin X, Dores MR, Smith TH, Grimsey N, Abagyan R, Trejo J, Kufareva I, Fuster MM, Salanga CL, Handel TM. Kawamura T, et al. Among authors: stephens b. PLoS One. 2014 Jan 28;9(1):e81454. doi: 10.1371/journal.pone.0081454. eCollection 2014. PLoS One. 2014. PMID: 24489642 Free PMC article.

2

Stoichiometry and geometry of the CXC chemokine receptor 4 complex with CXC ligand 12: molecular modeling and experimental validation.

Kufareva I, Stephens BS, Holden LG, Qin L, Zhao C, Kawamura T, Abagyan R, Handel TM. Kufareva I, et al. Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):E5363-72. doi: 10.1073/pnas.1417037111. Epub 2014 Dec 2. Proc Natl Acad Sci U S A. 2014. PMID: 25468967 Free PMC article.

3

Structural basis of ligand interaction with atypical chemokine receptor 3.

Gustavsson M, Wang L, van Gils N, Stephens BS, Zhang P, Schall TJ, Yang S, Abagyan R, Chance MR, Kufareva I, Handel TM. Gustavsson M, et al. Nat Commun. 2017 Jan 18;8:14135. doi: 10.1038/ncomms14135. Nat Commun. 2017. PMID: 28098154 Free PMC article.

4

What Do Structures Tell Us About Chemokine Receptor Function and Antagonism?

Kufareva I, Gustavsson M, Zheng Y, Stephens BS, Handel TM. Kufareva I, et al. Annu Rev Biophys. 2017 May 22;46:175-198. doi: 10.1146/annurev-biophys-051013-022942. Annu Rev Biophys. 2017. PMID: 28532213 Free PMC article. Review.

5

Crosslinking-guided geometry of a complete CXC receptor-chemokine complex and the basis of chemokine subfamily selectivity.

Ngo T, Stephens BS, Gustavsson M, Holden LG, Abagyan R, Handel TM, Kufareva I. Ngo T, et al. PLoS Biol. 2020 Apr 9;18(4):e3000656. doi: 10.1371/journal.pbio.3000656. eCollection 2020 Apr. PLoS Biol. 2020. PMID: 32271748 Free PMC article.

6

Functional anatomy of the full-length CXCR4-CXCL12 complex systematically dissected by quantitative model-guided mutagenesis.

Stephens BS, Ngo T, Kufareva I, Handel TM. Stephens BS, et al. Sci Signal. 2020 Jul 14;13(640):eaay5024. doi: 10.1126/scisignal.aay5024. Sci Signal. 2020. PMID: 32665413 Free PMC article.

7

Chemokine receptor oligomerization and allostery.

Stephens B, Handel TM. Stephens B, et al. Prog Mol Biol Transl Sci. 2013;115:375-420. doi: 10.1016/B978-0-12-394587-7.00009-9. Prog Mol Biol Transl Sci. 2013. PMID: 23415099 Free PMC article. Review.

8

A novel approach to quantify G-protein-coupled receptor dimerization equilibrium using bioluminescence resonance energy transfer.

Kufareva I, Stephens B, Gilliland CT, Wu B, Fenalti G, Hamel D, Stevens RC, Abagyan R, Handel TM. Kufareva I, et al. Among authors: stephens b. Methods Mol Biol. 2013;1013:93-127. doi: 10.1007/978-1-62703-426-5_7. Methods Mol Biol. 2013. PMID: 23625495 Free PMC article.

9

Sulfopeptide probes of the CXCR4/CXCL12 interface reveal oligomer-specific contacts and chemokine allostery.

Ziarek JJ, Getschman AE, Butler SJ, Taleski D, Stephens B, Kufareva I, Handel TM, Payne RJ, Volkman BF. Ziarek JJ, et al. Among authors: stephens b. ACS Chem Biol. 2013 Sep 20;8(9):1955-63. doi: 10.1021/cb400274z. Epub 2013 Jun 26. ACS Chem Biol. 2013. PMID: 23802178 Free PMC article.

10

A Tyrosine Switch on NEDD4-2 E3 Ligase Transmits GPCR Inflammatory Signaling.

Grimsey NJ, Narala R, Rada CC, Mehta S, Stephens BS, Kufareva I, Lapek J, Gonzalez DJ, Handel TM, Zhang J, Trejo J. Grimsey NJ, et al. Cell Rep. 2018 Sep 18;24(12):3312-3323.e5. doi: 10.1016/j.celrep.2018.08.061. Cell Rep. 2018. PMID: 30232011 Free PMC article.

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