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Page 1
Lipoxin A4 yields an electrophilic 15-oxo metabolite that mediates FPR2 receptor-independent anti-inflammatory signaling.
Koudelka A, Buchan GJ, Cechova V, O'Brien JP, Liu H, Woodcock SR, Mullett SJ, Zhang C, Freeman BA, Gelhaus SL. Koudelka A, et al. Among authors: buchan gj. bioRxiv [Preprint]. 2024 Feb 7:2024.02.06.579101. doi: 10.1101/2024.02.06.579101. bioRxiv. 2024. Update in: J Lipid Res. 2024 Nov 19;66(1):100705. doi: 10.1016/j.jlr.2024.100705 PMID: 38370667 Free PMC article. Updated. Preprint.
Nitroalkene fatty acids modulate bile acid metabolism and lung function in obese asthma.
Manni ML, Heinrich VA, Buchan GJ, O'Brien JP, Uvalle C, Cechova V, Koudelka A, Ukani D, Rawas-Qalaji M, Oury TD, Hart R, Ellgass M, Mullett SJ, Fajt ML, Wenzel SE, Holguin F, Freeman BA, Wendell SG. Manni ML, et al. Among authors: buchan gj. Sci Rep. 2021 Sep 7;11(1):17788. doi: 10.1038/s41598-021-96471-9. Sci Rep. 2021. PMID: 34493738 Free PMC article.
Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling.
Hansen AL, Buchan GJ, Rühl M, Mukai K, Salvatore SR, Ogawa E, Andersen SD, Iversen MB, Thielke AL, Gunderstofte C, Motwani M, Møller CT, Jakobsen AS, Fitzgerald KA, Roos J, Lin R, Maier TJ, Goldbach-Mansky R, Miner CA, Qian W, Miner JJ, Rigby RE, Rehwinkel J, Jakobsen MR, Arai H, Taguchi T, Schopfer FJ, Olagnier D, Holm CK. Hansen AL, et al. Among authors: buchan gj. Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7768-E7775. doi: 10.1073/pnas.1806239115. Epub 2018 Jul 30. Proc Natl Acad Sci U S A. 2018. PMID: 30061387 Free PMC article.
Nitro-fatty acid formation and metabolism.
Buchan GJ, Bonacci G, Fazzari M, Salvatore SR, Gelhaus Wendell S. Buchan GJ, et al. Nitric Oxide. 2018 Sep 1;79:38-44. doi: 10.1016/j.niox.2018.07.003. Epub 2018 Jul 10. Nitric Oxide. 2018. PMID: 30006146 Free PMC article. Review.