Wu JT - Search Results

1

Preclinical drug metabolism and pharmacokinetics, and prediction of human pharmacokinetics and efficacious dose of the investigational Aurora A kinase inhibitor alisertib (MLN8237).

Yang JJ, Li Y, Chakravarty A, Lu C, Xia CQ, Chen S, Pusalkar S, Zhang M, Ecsedy J, Manfredi MG, Wu JT, Shyu WC, Balani SK. Yang JJ, et al. Among authors: wu jt. Drug Metab Lett. 2014 Jul;7(2):96-104. doi: 10.2174/1872312807666131229122359. Drug Metab Lett. 2014. PMID: 24484538

2

P-glycoprotein and breast cancer resistance protein affect disposition of tandutinib, a tyrosine kinase inhibitor.

Yang JJ, Milton MN, Yu S, Liao M, Liu N, Wu JT, Gan L, Balani SK, Lee FW, Prakash S, Xia CQ. Yang JJ, et al. Among authors: wu jt. Drug Metab Lett. 2010 Dec;4(4):201-12. doi: 10.2174/187231210792928279. Drug Metab Lett. 2010. PMID: 20670210

3

An indirect screen for brain uptake of 1,2-diarylethane melanocortin 4 receptor antagonists in rats.

Yin W, Gan LS, Wu JT, Balani SK, Yang H, Lee FW. Yin W, et al. Among authors: wu jt. Drug Metab Lett. 2007 Aug;1(3):195-8. doi: 10.2174/187231207781369753. Drug Metab Lett. 2007. PMID: 19356043

4

Effective dosing regimen of 1-aminobenzotriazole for inhibition of antipyrine clearance in guinea pigs and mice using serial sampling.

Balani SK, Li P, Nguyen J, Cardoza K, Zeng H, Mu DX, Wu JT, Gan LS, Lee FW. Balani SK, et al. Among authors: wu jt. Drug Metab Dispos. 2004 Oct;32(10):1092-5. doi: 10.1124/dmd.104.000349. Epub 2004 Jun 24. Drug Metab Dispos. 2004. PMID: 15217988

5

Strategy of utilizing in vitro and in vivo ADME tools for lead optimization and drug candidate selection.

Balani SK, Miwa GT, Gan LS, Wu JT, Lee FW. Balani SK, et al. Among authors: wu jt. Curr Top Med Chem. 2005;5(11):1033-8. doi: 10.2174/156802605774297038. Curr Top Med Chem. 2005. PMID: 16181128 Review.

6

Evaluation of microdosing to assess pharmacokinetic linearity in rats using liquid chromatography-tandem mass spectrometry.

Balani SK, Nagaraja NV, Qian MG, Costa AO, Daniels JS, Yang H, Shimoga PR, Wu JT, Gan LS, Lee FW, Miwa GT. Balani SK, et al. Among authors: wu jt. Drug Metab Dispos. 2006 Mar;34(3):384-8. doi: 10.1124/dmd.105.007195. Epub 2005 Dec 2. Drug Metab Dispos. 2006. PMID: 16326814

7

Evaluation of surrogate matrices for standard curve preparation in tissue bioanalysis.

Chen S, Wu JT, Huang R. Chen S, et al. Among authors: wu jt. Bioanalysis. 2012 Nov;4(21):2579-87. doi: 10.4155/bio.12.237. Bioanalysis. 2012. PMID: 23173793

8

The use of a rapid MS-based method for the quantification of the CYP 3A4 protein directly from hepatocyte cell lysate for CYP induction studies.

Xu L, Ma B, Yu S, Xia C, Wu JT. Xu L, et al. Among authors: wu jt. Bioanalysis. 2014;6(24):3271-82. doi: 10.4155/bio.14.228. Bioanalysis. 2014. PMID: 25534785

9

Biotransformation of [¹⁴C]-ixazomib in patients with advanced solid tumors: characterization of metabolite profiles in plasma, urine, and feces.

Pusalkar S, Plesescu M, Gupta N, Hanley M, Venkatakrishnan K, Wu JT, Xia C, Zhang X, Chowdhury S. Pusalkar S, et al. Among authors: wu jt. Cancer Chemother Pharmacol. 2018 Nov;82(5):803-814. doi: 10.1007/s00280-018-3671-z. Epub 2018 Aug 20. Cancer Chemother Pharmacol. 2018. PMID: 30128949 Clinical Trial.

10

Validation of a high-throughput absorption, distribution, metabolism, and excretion (ADME) system and results for 60 literature compounds.

Yan Z, Lu C, Wu JT, Elvebak L, Brockman A. Yan Z, et al. Among authors: wu jt. Rapid Commun Mass Spectrom. 2005;19(9):1191-9. doi: 10.1002/rcm.1903. Rapid Commun Mass Spectrom. 2005. PMID: 15818724

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