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Activation and regulation of pathogen sensor RIG-I.
Patel JR, García-Sastre A. Patel JR, et al. Cytokine Growth Factor Rev. 2014 Oct;25(5):513-23. doi: 10.1016/j.cytogfr.2014.08.005. Epub 2014 Aug 23. Cytokine Growth Factor Rev. 2014. PMID: 25212896 Review.
Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection.
Aguirre S, Luthra P, Sanchez-Aparicio MT, Maestre AM, Patel J, Lamothe F, Fredericks AC, Tripathi S, Zhu T, Pintado-Silva J, Webb LG, Bernal-Rubio D, Solovyov A, Greenbaum B, Simon V, Basler CF, Mulder LC, García-Sastre A, Fernandez-Sesma A. Aguirre S, et al. Nat Microbiol. 2017 Mar 27;2:17037. doi: 10.1038/nmicrobiol.2017.37. Nat Microbiol. 2017. PMID: 28346446 Free PMC article.
Three-stranded antiviral attack.
Patel JR, García-Sastre A. Patel JR, et al. Elife. 2014 Jan 1;3:e02369. doi: 10.7554/eLife.02369. Elife. 2014. PMID: 24596154 Free PMC article.
Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response.
Rajsbaum R, Versteeg GA, Schmid S, Maestre AM, Belicha-Villanueva A, Martínez-Romero C, Patel JR, Morrison J, Pisanelli G, Miorin L, Laurent-Rolle M, Moulton HM, Stein DA, Fernandez-Sesma A, tenOever BR, García-Sastre A. Rajsbaum R, et al. Among authors: patel jr. Immunity. 2014 Jun 19;40(6):880-95. doi: 10.1016/j.immuni.2014.04.018. Epub 2014 May 29. Immunity. 2014. PMID: 24882218 Free PMC article.
294 results