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447 results

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Page 1
The influence of rare genetic variation in SLC30A8 on diabetes incidence and β-cell function.
Billings LK, Jablonski KA, Ackerman RJ, Taylor A, Fanelli RR, McAteer JB, Guiducci C, Delahanty LM, Dabelea D, Kahn SE, Franks PW, Hanson RL, Maruthur NM, Shuldiner AR, Mayer-Davis EJ, Knowler WC, Florez JC; Diabetes Prevention Program Research Group, Rockville. Billings LK, et al. Among authors: florez jc. J Clin Endocrinol Metab. 2014 May;99(5):E926-30. doi: 10.1210/jc.2013-2378. Epub 2014 Jan 28. J Clin Endocrinol Metab. 2014. PMID: 24471563 Free PMC article.
Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals.
Saxena R, Gianniny L, Burtt NP, Lyssenko V, Giuducci C, Sjögren M, Florez JC, Almgren P, Isomaa B, Orho-Melander M, Lindblad U, Daly MJ, Tuomi T, Hirschhorn JN, Ardlie KG, Groop LC, Altshuler D. Saxena R, et al. Among authors: florez jc. Diabetes. 2006 Oct;55(10):2890-5. doi: 10.2337/db06-0381. Diabetes. 2006. PMID: 17003358
Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and response to troglitazone.
Florez JC, Jablonski KA, Sun MW, Bayley N, Kahn SE, Shamoon H, Hamman RF, Knowler WC, Nathan DM, Altshuler D; Diabetes Prevention Program Research Group. Florez JC, et al. J Clin Endocrinol Metab. 2007 Apr;92(4):1502-9. doi: 10.1210/jc.2006-2275. Epub 2007 Jan 9. J Clin Endocrinol Metab. 2007. PMID: 17213274 Free PMC article. Clinical Trial.
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.
Diabetes Genetics Initiative of Broad Institute of Harvard and MIT, Lund University, and Novartis Institutes of BioMedical Research; Saxena R, Voight BF, Lyssenko V, Burtt NP, de Bakker PI, Chen H, Roix JJ, Kathiresan S, Hirschhorn JN, Daly MJ, Hughes TE, Groop L, Altshuler D, Almgren P, Florez JC, Meyer J, Ardlie K, Bengtsson Boström K, Isomaa B, Lettre G, Lindblad U, Lyon HN, Melander O, Newton-Cheh C, Nilsson P, Orho-Melander M, Råstam L, Speliotes EK, Taskinen MR, Tuomi T, Guiducci C, Berglund A, Carlson J, Gianniny L, Hackett R, Hall L, Holmkvist J, Laurila E, Sjögren M, Sterner M, Surti A, Svensson M, Svensson M, Tewhey R, Blumenstiel B, Parkin M, Defelice M, Barry R, Brodeur W, Camarata J, Chia N, Fava M, Gibbons J, Handsaker B, Healy C, Nguyen K, Gates C, Sougnez C, Gage D, Nizzari M, Gabriel SB, Chirn GW, Ma Q, Parikh H, Richardson D, Ricke D, Purcell S. Diabetes Genetics Initiative of Broad Institute of Harvard and MIT, Lund University, and Novartis Institutes of BioMedical Research, et al. Among authors: florez jc. Science. 2007 Jun 1;316(5829):1331-6. doi: 10.1126/science.1142358. Epub 2007 Apr 26. Science. 2007. PMID: 17463246
The new type 2 diabetes gene TCF7L2.
Florez JC. Florez JC. Curr Opin Clin Nutr Metab Care. 2007 Jul;10(4):391-6. doi: 10.1097/MCO.0b013e3281e2c9be. Curr Opin Clin Nutr Metab Care. 2007. PMID: 17563454 Review.
447 results