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The scl +18/19 stem cell enhancer is not required for hematopoiesis: identification of a 5' bifunctional hematopoietic-endothelial enhancer bound by Fli-1 and Elf-1.
Göttgens B, Broccardo C, Sanchez MJ, Deveaux S, Murphy G, Göthert JR, Kotsopoulou E, Kinston S, Delaney L, Piltz S, Barton LM, Knezevic K, Erber WN, Begley CG, Frampton J, Green AR. Göttgens B, et al. Mol Cell Biol. 2004 Mar;24(5):1870-83. doi: 10.1128/MCB.24.5.1870-1883.2004. Mol Cell Biol. 2004. PMID: 14966269 Free PMC article.
Transcriptional regulatory networks in haematopoiesis.
Miranda-Saavedra D, Göttgens B. Miranda-Saavedra D, et al. Among authors: gottgens b. Curr Opin Genet Dev. 2008 Dec;18(6):530-5. doi: 10.1016/j.gde.2008.09.001. Epub 2008 Oct 7. Curr Opin Genet Dev. 2008. PMID: 18838119 Review.
The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development.
Wilson NK, Miranda-Saavedra D, Kinston S, Bonadies N, Foster SD, Calero-Nieto F, Dawson MA, Donaldson IJ, Dumon S, Frampton J, Janky R, Sun XH, Teichmann SA, Bannister AJ, Göttgens B. Wilson NK, et al. Among authors: gottgens b. Blood. 2009 May 28;113(22):5456-65. doi: 10.1182/blood-2009-01-200048. Epub 2009 Apr 3. Blood. 2009. PMID: 19346495 Free article.
Ontogeny of haematopoiesis: recent advances and open questions.
Ottersbach K, Smith A, Wood A, Göttgens B. Ottersbach K, et al. Among authors: gottgens b. Br J Haematol. 2010 Feb;148(3):343-55. doi: 10.1111/j.1365-2141.2009.07953.x. Epub 2009 Oct 22. Br J Haematol. 2010. PMID: 19863543 Free article. Review.
Gfi1 expression is controlled by five distinct regulatory regions spread over 100 kilobases, with Scl/Tal1, Gata2, PU.1, Erg, Meis1, and Runx1 acting as upstream regulators in early hematopoietic cells.
Wilson NK, Timms RT, Kinston SJ, Cheng YH, Oram SH, Landry JR, Mullender J, Ottersbach K, Gottgens B. Wilson NK, et al. Among authors: gottgens b. Mol Cell Biol. 2010 Aug;30(15):3853-63. doi: 10.1128/MCB.00032-10. Epub 2010 Jun 1. Mol Cell Biol. 2010. PMID: 20516218 Free PMC article.
331 results