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Metalloproteases meprin α and meprin β are C- and N-procollagen proteinases important for collagen assembly and tensile strength.
Broder C, Arnold P, Vadon-Le Goff S, Konerding MA, Bahr K, Müller S, Overall CM, Bond JS, Koudelka T, Tholey A, Hulmes DJ, Moali C, Becker-Pauly C. Broder C, et al. Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14219-24. doi: 10.1073/pnas.1305464110. Epub 2013 Aug 12. Proc Natl Acad Sci U S A. 2013. PMID: 23940311 Free PMC article.
The substrate degradome of meprin metalloproteases reveals an unexpected proteolytic link between meprin β and ADAM10.
Jefferson T, Auf dem Keller U, Bellac C, Metz VV, Broder C, Hedrich J, Ohler A, Maier W, Magdolen V, Sterchi E, Bond JS, Jayakumar A, Traupe H, Chalaris A, Rose-John S, Pietrzik CU, Postina R, Overall CM, Becker-Pauly C. Jefferson T, et al. Among authors: broder c. Cell Mol Life Sci. 2013 Jan;70(2):309-33. doi: 10.1007/s00018-012-1106-2. Epub 2012 Sep 1. Cell Mol Life Sci. 2013. PMID: 22940918 Free PMC article.
Proteomic analyses reveal an acidic prime side specificity for the astacin metalloprotease family reflected by physiological substrates.
Becker-Pauly C, Barré O, Schilling O, Auf dem Keller U, Ohler A, Broder C, Schütte A, Kappelhoff R, Stöcker W, Overall CM. Becker-Pauly C, et al. Among authors: broder c. Mol Cell Proteomics. 2011 Sep;10(9):M111.009233. doi: 10.1074/mcp.M111.009233. Epub 2011 Jun 21. Mol Cell Proteomics. 2011. PMID: 21693781 Free PMC article.
Short-term TNFα shedding is independent of cytoplasmic phosphorylation or furin cleavage of ADAM17.
Schwarz J, Broder C, Helmstetter A, Schmidt S, Yan I, Müller M, Schmidt-Arras D, Becker-Pauly C, Koch-Nolte F, Mittrücker HW, Rabe B, Rose-John S, Chalaris A. Schwarz J, et al. Among authors: broder c. Biochim Biophys Acta. 2013 Dec;1833(12):3355-3367. doi: 10.1016/j.bbamcr.2013.10.005. Epub 2013 Oct 14. Biochim Biophys Acta. 2013. PMID: 24135057 Free article.
Establishing an immune correlate of protection for Nipah virus in nonhuman primates.
Leyva-Grado VH, Promeneur D, Agans KN, Lazaro GG, Borisevich V, Deer DJ, Luckay A, Egan M, Dimitrov AS, Small B, Broder CC, Cross RW, Hamm S, Geisbert TW. Leyva-Grado VH, et al. Among authors: broder cc. NPJ Vaccines. 2024 Dec 19;9(1):244. doi: 10.1038/s41541-024-01036-2. NPJ Vaccines. 2024. PMID: 39702562 Free PMC article.
Ecological and Reproductive Cycles Drive Henipavirus Seroprevalence in the African Straw-Coloured Fruit Bat (Eidolon helvum).
Juman MM, Gibson L, Suu-Ire RD, Languon S, Quaye O, Fleischer G, Asumah S, Jolma ER, Gautam A, Sterling SL, Yan L, Broder CC, Laing ED, Wood JLN, Cunningham AA, Restif O. Juman MM, et al. Among authors: broder cc. Ecol Evol. 2024 Nov 11;14(11):e70555. doi: 10.1002/ece3.70555. eCollection 2024 Nov. Ecol Evol. 2024. PMID: 39530036 Free PMC article.
246 results