Miller JH - Search Results

1

Structural basis of microtubule stabilization by laulimalide and peloruside A.

Prota AE, Bargsten K, Northcote PT, Marsh M, Altmann KH, Miller JH, Díaz JF, Steinmetz MO. Prota AE, et al. Among authors: miller jh. Angew Chem Int Ed Engl. 2014 Feb 3;53(6):1621-5. doi: 10.1002/anie.201307749. Epub 2014 Jan 27. Angew Chem Int Ed Engl. 2014. PMID: 24470331

2

The novel cytotoxic sponge metabolite peloruside A, structurally similar to bryostatin-1, has unique bioactivity independent of protein kinase C.

Hood KA, Bäckström BT, West LM, Northcote PT, Berridge MV, Miller JH. Hood KA, et al. Among authors: miller jh. Anticancer Drug Des. 2001 Apr-Jun;16(2-3):155-66. Anticancer Drug Des. 2001. PMID: 11962513

3

Peloruside A, a novel antimitotic agent with paclitaxel-like microtubule- stabilizing activity.

Hood KA, West LM, Rouwé B, Northcote PT, Berridge MV, Wakefield SJ, Miller JH. Hood KA, et al. Among authors: miller jh. Cancer Res. 2002 Jun 15;62(12):3356-60. Cancer Res. 2002. PMID: 12067973

4

Peloruside A does not bind to the taxoid site on beta-tubulin and retains its activity in multidrug-resistant cell lines.

Gaitanos TN, Buey RM, Díaz JF, Northcote PT, Teesdale-Spittle P, Andreu JM, Miller JH. Gaitanos TN, et al. Among authors: miller jh. Cancer Res. 2004 Aug 1;64(15):5063-7. doi: 10.1158/0008-5472.CAN-04-0771. Cancer Res. 2004. PMID: 15289305

5

Peloruside A enhances apoptosis in H-ras-transformed cells and is cytotoxic to proliferating T cells.

Miller JH, Rouwé B, Gaitanos TN, Hood KA, Crume KP, Bäckström BT, La Flamme AC, Berridge MV, Northcote PT. Miller JH, et al. Apoptosis. 2004 Nov;9(6):785-96. doi: 10.1023/B:APPT.0000045789.54694.cf. Apoptosis. 2004. PMID: 15505421

6

Synergistic effects of peloruside A and laulimalide with taxoid site drugs, but not with each other, on tubulin assembly.

Hamel E, Day BW, Miller JH, Jung MK, Northcote PT, Ghosh AK, Curran DP, Cushman M, Nicolaou KC, Paterson I, Sorensen EJ. Hamel E, et al. Among authors: miller jh. Mol Pharmacol. 2006 Nov;70(5):1555-64. doi: 10.1124/mol.106.027847. Epub 2006 Aug 3. Mol Pharmacol. 2006. PMID: 16887932

7

Peloruside A synergizes with other microtubule stabilizing agents in cultured cancer cell lines.

Wilmes A, Bargh K, Kelly C, Northcote PT, Miller JH. Wilmes A, et al. Among authors: miller jh. Mol Pharm. 2007 Mar-Apr;4(2):269-80. doi: 10.1021/mp060101p. Mol Pharm. 2007. PMID: 17397239

8

Delaying the onset of experimental autoimmune encephalomyelitis with the microtubule-stabilizing compounds, paclitaxel and Peloruside A.

Crume KP, O'Sullivan D, Miller JH, Northcote PT, La Flamme AC. Crume KP, et al. Among authors: miller jh. J Leukoc Biol. 2009 Oct;86(4):949-58. doi: 10.1189/jlb.0908541. Epub 2009 Aug 4. J Leukoc Biol. 2009. PMID: 19654226

9

Microtubule-stabilizing activity of zampanolide, a potent macrolide isolated from the Tongan marine sponge Cacospongia mycofijiensis.

Field JJ, Singh AJ, Kanakkanthara A, Halafihi T, Northcote PT, Miller JH. Field JJ, et al. Among authors: miller jh. J Med Chem. 2009 Nov 26;52(22):7328-32. doi: 10.1021/jm901249g. J Med Chem. 2009. PMID: 19877653

10

Peloruside B, a potent antitumor macrolide from the New Zealand marine sponge Mycale hentscheli: isolation, structure, total synthesis, and bioactivity.

Singh AJ, Xu CX, Xu X, West LM, Wilmes A, Chan A, Hamel E, Miller JH, Northcote PT, Ghosh AK. Singh AJ, et al. Among authors: miller jh. J Org Chem. 2010 Jan 1;75(1):2-10. doi: 10.1021/jo9021265. J Org Chem. 2010. PMID: 19957922 Free PMC article.

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