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Identification and characterization of the constituent human serum antibodies elicited by vaccination.
Lavinder JJ, Wine Y, Giesecke C, Ippolito GC, Horton AP, Lungu OI, Hoi KH, DeKosky BJ, Murrin EM, Wirth MM, Ellington AD, Dörner T, Marcotte EM, Boutz DR, Georgiou G. Lavinder JJ, et al. Among authors: giesecke c. Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2259-64. doi: 10.1073/pnas.1317793111. Epub 2014 Jan 27. Proc Natl Acad Sci U S A. 2014. PMID: 24469811 Free PMC article.
High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire.
DeKosky BJ, Ippolito GC, Deschner RP, Lavinder JJ, Wine Y, Rawlings BM, Varadarajan N, Giesecke C, Dörner T, Andrews SF, Wilson PC, Hunicke-Smith SP, Willson CG, Ellington AD, Georgiou G. DeKosky BJ, et al. Among authors: giesecke c. Nat Biotechnol. 2013 Feb;31(2):166-9. doi: 10.1038/nbt.2492. Epub 2013 Jan 20. Nat Biotechnol. 2013. PMID: 23334449 Free PMC article.
Mechanisms of B cell autoimmunity in SLE.
Dörner T, Giesecke C, Lipsky PE. Dörner T, et al. Among authors: giesecke c. Arthritis Res Ther. 2011;13(5):243. doi: 10.1186/ar3433. Epub 2011 Oct 27. Arthritis Res Ther. 2011. PMID: 22078750 Free PMC article. Review.
The anti-CD74 humanized monoclonal antibody, milatuzumab, which targets the invariant chain of MHC II complexes, alters B-cell proliferation, migration, and adhesion molecule expression.
Frölich D, Blassfeld D, Reiter K, Giesecke C, Daridon C, Mei HE, Burmester GR, Goldenberg DM, Salama A, Dörner T. Frölich D, et al. Among authors: giesecke c. Arthritis Res Ther. 2012 Mar 9;14(2):R54. doi: 10.1186/ar3767. Arthritis Res Ther. 2012. PMID: 22404985 Free PMC article.
A unique population of IgG-expressing plasma cells lacking CD19 is enriched in human bone marrow.
Mei HE, Wirries I, Frölich D, Brisslert M, Giesecke C, Grün JR, Alexander T, Schmidt S, Luda K, Kühl AA, Engelmann R, Dürr M, Scheel T, Bokarewa M, Perka C, Radbruch A, Dörner T. Mei HE, et al. Among authors: giesecke c. Blood. 2015 Mar 12;125(11):1739-48. doi: 10.1182/blood-2014-02-555169. Epub 2015 Jan 8. Blood. 2015. PMID: 25573986 Free article.
22 results