Knudsen LB - Search Results

1

GLP-1 receptor localization in monkey and human tissue: novel distribution revealed with extensively validated monoclonal antibody.

Pyke C, Heller RS, Kirk RK, Ørskov C, Reedtz-Runge S, Kaastrup P, Hvelplund A, Bardram L, Calatayud D, Knudsen LB. Pyke C, et al. Among authors: knudsen lb. Endocrinology. 2014 Apr;155(4):1280-90. doi: 10.1210/en.2013-1934. Epub 2014 Jan 27. Endocrinology. 2014. PMID: 24467746

2

The truncated metabolite GLP-2 (3-33) interacts with the GLP-2 receptor as a partial agonist.

Thulesen J, Knudsen LB, Hartmann B, Hastrup S, Kissow H, Jeppesen PB, Ørskov C, Holst JJ, Poulsen SS. Thulesen J, et al. Among authors: knudsen lb. Regul Pept. 2002 Jan 15;103(1):9-15. doi: 10.1016/s0167-0115(01)00316-0. Regul Pept. 2002. PMID: 11738243

3

The long-acting GLP-1 derivative NN2211 ameliorates glycemia and increases beta-cell mass in diabetic mice.

Rolin B, Larsen MO, Gotfredsen CF, Deacon CF, Carr RD, Wilken M, Knudsen LB. Rolin B, et al. Among authors: knudsen lb. Am J Physiol Endocrinol Metab. 2002 Oct;283(4):E745-52. doi: 10.1152/ajpendo.00030.2002. Am J Physiol Endocrinol Metab. 2002. PMID: 12217892 Free article.

4

Liraglutide, a long-acting human glucagon-like peptide 1 analog, improves glucose homeostasis in marginal mass islet transplantation in mice.

Merani S, Truong W, Emamaullee JA, Toso C, Knudsen LB, Shapiro AM. Merani S, et al. Among authors: knudsen lb. Endocrinology. 2008 Sep;149(9):4322-8. doi: 10.1210/en.2008-0501. Epub 2008 May 29. Endocrinology. 2008. PMID: 18511515

5

Expression of the GLP-1 receptor in mouse, rat, and human pancreas.

Tornehave D, Kristensen P, Rømer J, Knudsen LB, Heller RS. Tornehave D, et al. Among authors: knudsen lb. J Histochem Cytochem. 2008 Sep;56(9):841-51. doi: 10.1369/jhc.2008.951319. Epub 2008 Jun 9. J Histochem Cytochem. 2008. PMID: 18541709 Free PMC article.

6

Crystal structure of glucagon-like peptide-1 in complex with the extracellular domain of the glucagon-like peptide-1 receptor.

Underwood CR, Garibay P, Knudsen LB, Hastrup S, Peters GH, Rudolph R, Reedtz-Runge S. Underwood CR, et al. Among authors: knudsen lb. J Biol Chem. 2010 Jan 1;285(1):723-30. doi: 10.1074/jbc.M109.033829. Epub 2009 Oct 27. J Biol Chem. 2010. PMID: 19861722 Free PMC article.

7

Liraglutide, but not vildagliptin, restores normoglycaemia and insulin content in the animal model of type 2 diabetes, Psammomys obesus.

Vedtofte L, Bodvarsdottir TB, Gotfredsen CF, Karlsen AE, Knudsen LB, Heller RS. Vedtofte L, et al. Among authors: knudsen lb. Regul Pept. 2010 Feb 25;160(1-3):106-14. doi: 10.1016/j.regpep.2009.12.005. Epub 2009 Dec 30. Regul Pept. 2010. PMID: 20005262

8

Long-term characterization of the diet-induced obese and diet-resistant rat model: a polygenetic rat model mimicking the human obesity syndrome.

Madsen AN, Hansen G, Paulsen SJ, Lykkegaard K, Tang-Christensen M, Hansen HS, Levin BE, Larsen PJ, Knudsen LB, Fosgerau K, Vrang N. Madsen AN, et al. Among authors: knudsen lb. J Endocrinol. 2010 Sep;206(3):287-96. doi: 10.1677/JOE-10-0004. Epub 2010 May 27. J Endocrinol. 2010. PMID: 20508079

9

Transmembrane α-helix 2 and 7 are important for small molecule-mediated activation of the GLP-1 receptor.

Rye Underwood C, Møller Knudsen S, Schjellerup Wulff B, Bräuner-Osborne H, Lau J, Knudsen LB, Peters GH, Reedtz-Runge S. Rye Underwood C, et al. Among authors: knudsen lb. Pharmacology. 2011;88(5-6):340-8. doi: 10.1159/000334338. Epub 2011 Nov 30. Pharmacology. 2011. PMID: 22134089

10

GLP-1 receptor agonists and the thyroid: C-cell effects in mice are mediated via the GLP-1 receptor and not associated with RET activation.

Madsen LW, Knauf JA, Gotfredsen C, Pilling A, Sjögren I, Andersen S, Andersen L, de Boer AS, Manova K, Barlas A, Vundavalli S, Nyborg NC, Knudsen LB, Moelck AM, Fagin JA. Madsen LW, et al. Among authors: knudsen lb. Endocrinology. 2012 Mar;153(3):1538-47. doi: 10.1210/en.2011-1864. Epub 2012 Jan 10. Endocrinology. 2012. PMID: 22234463 Free PMC article.

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