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Simultaneous targeting of IL-1 and IL-18 is required for protection against inflammatory and septic shock.
Vanden Berghe T, Demon D, Bogaert P, Vandendriessche B, Goethals A, Depuydt B, Vuylsteke M, Roelandt R, Van Wonterghem E, Vandenbroecke J, Choi SM, Meyer E, Krautwald S, Declercq W, Takahashi N, Cauwels A, Vandenabeele P. Vanden Berghe T, et al. Among authors: cauwels a. Am J Respir Crit Care Med. 2014 Feb 1;189(3):282-91. doi: 10.1164/rccm.201308-1535OC. Am J Respir Crit Care Med. 2014. PMID: 24456467
IL-17 produced by Paneth cells drives TNF-induced shock.
Takahashi N, Vanlaere I, de Rycke R, Cauwels A, Joosten LA, Lubberts E, van den Berg WB, Libert C. Takahashi N, et al. Among authors: cauwels a. J Exp Med. 2008 Aug 4;205(8):1755-61. doi: 10.1084/jem.20080588. Epub 2008 Jul 28. J Exp Med. 2008. PMID: 18663129 Free PMC article.
53 results