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A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog.
Hagelkruys A, Lagger S, Krahmer J, Leopoldi A, Artaker M, Pusch O, Zezula J, Weissmann S, Xie Y, Schöfer C, Schlederer M, Brosch G, Matthias P, Selfridge J, Lassmann H, Knoblich JA, Seiser C. Hagelkruys A, et al. Among authors: selfridge j. Development. 2014 Feb;141(3):604-616. doi: 10.1242/dev.100487. Development. 2014. PMID: 24449838 Free PMC article.
Toxicity of overexpressed MeCP2 is independent of HDAC3 activity.
Koerner MV, FitzPatrick L, Selfridge J, Guy J, De Sousa D, Tillotson R, Kerr A, Sun Z, Lazar MA, Lyst MJ, Bird A. Koerner MV, et al. Among authors: selfridge j. Genes Dev. 2018 Dec 1;32(23-24):1514-1524. doi: 10.1101/gad.320325.118. Epub 2018 Nov 21. Genes Dev. 2018. PMID: 30463906 Free PMC article.
The role of MeCP2 in the brain.
Guy J, Cheval H, Selfridge J, Bird A. Guy J, et al. Among authors: selfridge j. Annu Rev Cell Dev Biol. 2011;27:631-52. doi: 10.1146/annurev-cellbio-092910-154121. Epub 2011 Jun 29. Annu Rev Cell Dev Biol. 2011. PMID: 21721946 Review.
121 results