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A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog.
Hagelkruys A, Lagger S, Krahmer J, Leopoldi A, Artaker M, Pusch O, Zezula J, Weissmann S, Xie Y, Schöfer C, Schlederer M, Brosch G, Matthias P, Selfridge J, Lassmann H, Knoblich JA, Seiser C. Hagelkruys A, et al. Among authors: brosch g. Development. 2014 Feb;141(3):604-616. doi: 10.1242/dev.100487. Development. 2014. PMID: 24449838 Free PMC article.
Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis.
Winter M, Moser MA, Meunier D, Fischer C, Machat G, Mattes K, Lichtenberger BM, Brunmeir R, Weissmann S, Murko C, Humer C, Meischel T, Brosch G, Matthias P, Sibilia M, Seiser C. Winter M, et al. Among authors: brosch g. EMBO J. 2013 Dec 11;32(24):3176-91. doi: 10.1038/emboj.2013.243. Epub 2013 Nov 15. EMBO J. 2013. PMID: 24240174 Free PMC article.
A toolbox for class I HDACs reveals isoform specific roles in gene regulation and protein acetylation.
Hess L, Moos V, Lauber AA, Reiter W, Schuster M, Hartl N, Lackner D, Boenke T, Koren A, Guzzardo PM, Gundacker B, Riegler A, Vician P, Miccolo C, Leiter S, Chandrasekharan MB, Vcelkova T, Tanzer A, Jun JQ, Bradner J, Brosch G, Hartl M, Bock C, Bürckstümmer T, Kubicek S, Chiocca S, Bhaskara S, Seiser C. Hess L, et al. Among authors: brosch g. PLoS Genet. 2022 Aug 22;18(8):e1010376. doi: 10.1371/journal.pgen.1010376. eCollection 2022 Aug. PLoS Genet. 2022. PMID: 35994477 Free PMC article.
Histone deacetylase 1 can repress transcription by binding to Sp1.
Doetzlhofer A, Rotheneder H, Lagger G, Koranda M, Kurtev V, Brosch G, Wintersberger E, Seiser C. Doetzlhofer A, et al. Among authors: brosch g. Mol Cell Biol. 1999 Aug;19(8):5504-11. doi: 10.1128/MCB.19.8.5504. Mol Cell Biol. 1999. PMID: 10409740 Free PMC article.
Histone deacetylase 1 inactivation by an adenovirus early gene product.
Chiocca S, Kurtev V, Colombo R, Boggio R, Sciurpi MT, Brosch G, Seiser C, Draetta GF, Cotten M. Chiocca S, et al. Among authors: brosch g. Curr Biol. 2002 Apr 2;12(7):594-8. doi: 10.1016/s0960-9822(02)00720-0. Curr Biol. 2002. PMID: 11937030 Free article.
A Class 1 Histone Deacetylase with Potential as an Antifungal Target.
Bauer I, Varadarajan D, Pidroni A, Gross S, Vergeiner S, Faber B, Hermann M, Tribus M, Brosch G, Graessle S. Bauer I, et al. Among authors: brosch g. mBio. 2016 Nov 1;7(6):e00831-16. doi: 10.1128/mBio.00831-16. mBio. 2016. PMID: 27803184 Free PMC article.
74 results