Tilton RG - Search Results

1

IL-6 regulates extracellular matrix remodeling associated with aortic dilation in a fibrillin-1 hypomorphic mgR/mgR mouse model of severe Marfan syndrome.

Ju X, Ijaz T, Sun H, Lejeune W, Vargas G, Shilagard T, Recinos A 3rd, Milewicz DM, Brasier AR, Tilton RG. Ju X, et al. Among authors: tilton rg. J Am Heart Assoc. 2014 Jan 21;3(1):e000476. doi: 10.1161/JAHA.113.000476. J Am Heart Assoc. 2014. PMID: 24449804 Free PMC article.

2

Angiotensin II induces IL-6 expression and the Jak-STAT3 pathway in aortic adventitia of LDL receptor-deficient mice.

Recinos A 3rd, LeJeune WS, Sun H, Lee CY, Tieu BC, Lu M, Hou T, Boldogh I, Tilton RG, Brasier AR. Recinos A 3rd, et al. Among authors: tilton rg. Atherosclerosis. 2007 Sep;194(1):125-33. doi: 10.1016/j.atherosclerosis.2006.10.013. Epub 2006 Nov 15. Atherosclerosis. 2007. PMID: 17109863 Free PMC article.

3

An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice.

Tieu BC, Lee C, Sun H, Lejeune W, Recinos A 3rd, Ju X, Spratt H, Guo DC, Milewicz D, Tilton RG, Brasier AR. Tieu BC, et al. Among authors: tilton rg. J Clin Invest. 2009 Dec;119(12):3637-51. doi: 10.1172/JCI38308. Epub 2009 Nov 16. J Clin Invest. 2009. PMID: 19920349 Free PMC article.

4

Aortic adventitial fibroblasts participate in angiotensin-induced vascular wall inflammation and remodeling.

Tieu BC, Ju X, Lee C, Sun H, Lejeune W, Recinos A 3rd, Brasier AR, Tilton RG. Tieu BC, et al. Among authors: tilton rg. J Vasc Res. 2011;48(3):261-72. doi: 10.1159/000320358. Epub 2010 Nov 23. J Vasc Res. 2011. PMID: 21099231 Free PMC article.

5

Interleukin-6-signal transducer and activator of transcription-3 signaling mediates aortic dissections induced by angiotensin II via the T-helper lymphocyte 17-interleukin 17 axis in C57BL/6 mice.

Ju X, Ijaz T, Sun H, Ray S, Lejeune W, Lee C, Recinos A 3rd, Guo DC, Milewicz DM, Tilton RG, Brasier AR. Ju X, et al. Among authors: tilton rg. Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):1612-21. doi: 10.1161/ATVBAHA.112.301049. Epub 2013 May 16. Arterioscler Thromb Vasc Biol. 2013. PMID: 23685554 Free PMC article.

6

Cytokine amplification and macrophage effector functions in aortic inflammation and abdominal aortic aneurysm formation.

Ijaz T, Tilton RG, Brasier AR. Ijaz T, et al. Among authors: tilton rg. J Thorac Dis. 2016 Aug;8(8):E746-54. doi: 10.21037/jtd.2016.06.37. J Thorac Dis. 2016. PMID: 27619163 Free PMC article.

7

Generation and characterization of a novel transgenic mouse harboring conditional nuclear factor-kappa B/RelA knockout alleles.

Ijaz T, Wakamiya M, Sun H, Recinos A 3rd, Tilton RG, Brasier AR. Ijaz T, et al. Among authors: tilton rg. BMC Dev Biol. 2016 Sep 23;16(1):32. doi: 10.1186/s12861-016-0135-8. BMC Dev Biol. 2016. PMID: 27662828 Free PMC article.

8

Deletion of NF-κB/RelA in Angiotensin II-Sensitive Mesenchymal Cells Blocks Aortic Vascular Inflammation and Abdominal Aortic Aneurysm Formation.

Ijaz T, Sun H, Pinchuk IV, Milewicz DM, Tilton RG, Brasier AR. Ijaz T, et al. Among authors: tilton rg. Arterioscler Thromb Vasc Biol. 2017 Oct;37(10):1881-1890. doi: 10.1161/ATVBAHA.117.309863. Epub 2017 Aug 17. Arterioscler Thromb Vasc Biol. 2017. PMID: 28818856 Free PMC article.

9

RhoA mediates angiotensin II-induced phospho-Ser536 nuclear factor kappaB/RelA subunit exchange on the interleukin-6 promoter in VSMCs.

Cui R, Tieu B, Recinos A, Tilton RG, Brasier AR. Cui R, et al. Among authors: tilton rg. Circ Res. 2006 Sep 29;99(7):723-30. doi: 10.1161/01.RES.0000244015.10655.3f. Epub 2006 Sep 7. Circ Res. 2006. PMID: 16960103

10

Coordinate activities of BRD4 and CDK9 in the transcriptional elongation complex are required for TGFβ-induced Nox4 expression and myofibroblast transdifferentiation.

Ijaz T, Jamaluddin M, Zhao Y, Zhang Y, Jay J, Finnerty CC, Herndon DN, Tilton RG, Brasier AR. Ijaz T, et al. Among authors: tilton rg. Cell Death Dis. 2017 Feb 9;8(2):e2606. doi: 10.1038/cddis.2016.434. Cell Death Dis. 2017. PMID: 28182006 Free PMC article.

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