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Identification of SR2211: a potent synthetic RORγ-selective modulator.
Kumar N, Lyda B, Chang MR, Lauer JL, Solt LA, Burris TP, Kamenecka TM, Griffin PR. Kumar N, et al. Among authors: chang mr. ACS Chem Biol. 2012 Apr 20;7(4):672-7. doi: 10.1021/cb200496y. Epub 2012 Feb 13. ACS Chem Biol. 2012. PMID: 22292739 Free PMC article.
RORs in autoimmune disease.
Chang MR, Rosen H, Griffin PR. Chang MR, et al. Curr Top Microbiol Immunol. 2014;378:171-82. doi: 10.1007/978-3-319-05879-5_8. Curr Top Microbiol Immunol. 2014. PMID: 24728598 Review.
Antiobesity Effect of a Small Molecule Repressor of RORγ.
Chang MR, He Y, Khan TM, Kuruvilla DS, Garcia-Ordonez R, Corzo CA, Unger TJ, White DW, Khan S, Lin L, Cameron MD, Kamenecka TM, Griffin PR. Chang MR, et al. Mol Pharmacol. 2015 Jul;88(1):48-56. doi: 10.1124/mol.114.097485. Epub 2015 Apr 22. Mol Pharmacol. 2015. PMID: 25904554 Free PMC article.
SR2067 Reveals a Unique Kinetic and Structural Signature for PPARγ Partial Agonism.
van Marrewijk LM, Polyak SW, Hijnen M, Kuruvilla D, Chang MR, Shin Y, Kamenecka TM, Griffin PR, Bruning JB. van Marrewijk LM, et al. Among authors: chang mr. ACS Chem Biol. 2016 Jan 15;11(1):273-83. doi: 10.1021/acschembio.5b00580. Epub 2015 Dec 3. ACS Chem Biol. 2016. PMID: 26579553 Free PMC article.
Synthetic RORγt Agonists Enhance Protective Immunity.
Chang MR, Dharmarajan V, Doebelin C, Garcia-Ordonez RD, Novick SJ, Kuruvilla DS, Kamenecka TM, Griffin PR. Chang MR, et al. ACS Chem Biol. 2016 Apr 15;11(4):1012-8. doi: 10.1021/acschembio.5b00899. Epub 2016 Jan 25. ACS Chem Biol. 2016. PMID: 26785144 Free PMC article.
107 results