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Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation.
Yamane D, McGivern DR, Wauthier E, Yi M, Madden VJ, Welsch C, Antes I, Wen Y, Chugh PE, McGee CE, Widman DG, Misumi I, Bandyopadhyay S, Kim S, Shimakami T, Oikawa T, Whitmire JK, Heise MT, Dittmer DP, Kao CC, Pitson SM, Merrill AH Jr, Reid LM, Lemon SM. Yamane D, et al. Among authors: welsch c. Nat Med. 2014 Aug;20(8):927-35. doi: 10.1038/nm.3610. Epub 2014 Jul 27. Nat Med. 2014. PMID: 25064127 Free PMC article.
Extended interaction networks with HCV protease NS3-4A substrates explain the lack of adaptive capability against protease inhibitors.
Dultz G, Shimakami T, Schneider M, Murai K, Yamane D, Marion A, Zeitler TM, Stross C, Grimm C, Richter RM, Bäumer K, Yi M, Biondi RM, Zeuzem S, Tampé R, Antes I, Lange CM, Welsch C. Dultz G, et al. Among authors: welsch c. J Biol Chem. 2020 Oct 2;295(40):13862-13874. doi: 10.1074/jbc.RA120.013898. Epub 2020 Aug 3. J Biol Chem. 2020. PMID: 32747444 Free PMC article.
SPCS1-Dependent E2-p7 processing determines HCV Assembly efficiency.
Alzahrani N, Wu MJ, Sousa CF, Kalinina OV, Welsch C, Yi M. Alzahrani N, et al. Among authors: welsch c. PLoS Pathog. 2022 Feb 7;18(2):e1010310. doi: 10.1371/journal.ppat.1010310. eCollection 2022 Feb. PLoS Pathog. 2022. PMID: 35130329 Free PMC article.
295 results