Kong DX - Search Results

1

The discovery of a novel and selective inhibitor of PTP1B over TCPTP: 3D QSAR pharmacophore modeling, virtual screening, synthesis, and biological evaluation.

Ma Y, Jin YY, Wang YL, Wang RL, Lu XH, Kong DX, Xu WR. Ma Y, et al. Among authors: kong dx. Chem Biol Drug Des. 2014 Jun;83(6):697-709. doi: 10.1111/cbdd.12283. Chem Biol Drug Des. 2014. PMID: 24418013

2

Design potential selective inhibitors for treating cancer by targeting the Src homology 2 (SH2) domain-containing phosphatase 2 (Shp2) with core hopping approach.

Duan YQ, Ma Y, Wang XJ, Jin YY, Wang RL, Dong WL, Xu WR, Kong DX, Wang SQ. Duan YQ, et al. Among authors: kong dx. Protein Pept Lett. 2014 Jun;21(6):556-63. doi: 10.2174/0929866521666131223143913. Protein Pept Lett. 2014. PMID: 24364859

3

Discovery of two bombinin peptides with antimicrobial and anticancer activities from the skin secretion of Oriental fire-bellied toad, Bombina orientalis.

Zhou C, Wang Z, Peng X, Liu Y, Lin Y, Zhang Z, Qiu Y, Jin M, Wang R, Kong D. Zhou C, et al. Chem Biol Drug Des. 2018 Jan;91(1):50-61. doi: 10.1111/cbdd.13055. Epub 2017 Jul 19. Chem Biol Drug Des. 2018. PMID: 28636781

4

Discovery of Novel PI3Kδ Inhibitors Based on the p110δ Crystal Structure.

Jia W, Luo S, Zhao W, Xu W, Zhong Y, Kong D. Jia W, et al. Molecules. 2022 Sep 21;27(19):6211. doi: 10.3390/molecules27196211. Molecules. 2022. PMID: 36234743 Free PMC article.

5

Synthesis and antimetastatic effects of E-salignone amide derivatives.

Wang HL, Qin N, Liu J, Jin MN, Zhang X, Jin MH, Kong D, Jiang SD, Duan HQ. Wang HL, et al. Drug Dev Res. 2014 Mar;75(2):76-87. doi: 10.1002/ddr.21157. Epub 2013 Nov 15. Drug Dev Res. 2014. PMID: 24648170

6

Molecular characterization and bioactivity evaluation of two novel bombinin peptides from the skin secretion of Oriental fire-bellied toad, Bombina orientalis.

Peng X, Zhou C, Hou X, Liu Y, Wang Z, Peng X, Zhang Z, Wang R, Kong D. Peng X, et al. Amino Acids. 2018 Feb;50(2):241-253. doi: 10.1007/s00726-017-2509-z. Epub 2017 Nov 2. Amino Acids. 2018. PMID: 29098406

7

Discovery of a Novel Ubenimex Derivative as a First-in-Class Dual CD13/Proteasome Inhibitor for the Treatment of Cancer.

Zhang J, Sun S, Liu J, Zhang L, Guo D, Zhang N, Zhao J, Kong D, Xu T, Wang X, Xu W, Li X, Jiang Y. Zhang J, et al. Molecules. 2023 Aug 30;28(17):6343. doi: 10.3390/molecules28176343. Molecules. 2023. PMID: 37687169 Free PMC article.

8

JFCR39, a panel of 39 human cancer cell lines, and its application in the discovery and development of anticancer drugs.

Kong D, Yamori T. Kong D, et al. Bioorg Med Chem. 2012 Mar 15;20(6):1947-51. doi: 10.1016/j.bmc.2012.01.017. Epub 2012 Jan 21. Bioorg Med Chem. 2012. PMID: 22336246 Free article. Review.

9

In vitro antimetastatic effect of phosphatidylinositol 3-kinase inhibitor ZSTK474 on prostate cancer PC3 cells.

Zhao W, Guo W, Zhou Q, Ma SN, Wang R, Qiu Y, Jin M, Duan HQ, Kong D. Zhao W, et al. Int J Mol Sci. 2013 Jun 28;14(7):13577-91. doi: 10.3390/ijms140713577. Int J Mol Sci. 2013. PMID: 23812078 Free PMC article.

10

Nanoparticles induced by embedding self-assembling cassette into glucagon-like peptide 1 for improving in vivo stability.

Li Y, Cui T, Kong X, Yi X, Kong D, Zhang J, Liu C, Gong M. Li Y, et al. FASEB J. 2018 Jun;32(6):2992-3004. doi: 10.1096/fj.201701033RRR. Epub 2018 Jan 17. FASEB J. 2018. PMID: 29401602

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