Schaer DA - Search Results

1

GITR pathway activation abrogates tumor immune suppression through loss of regulatory T cell lineage stability.

Schaer DA, Budhu S, Liu C, Bryson C, Malandro N, Cohen A, Zhong H, Yang X, Houghton AN, Merghoub T, Wolchok JD. Schaer DA, et al. Cancer Immunol Res. 2013 Nov;1(5):320-31. doi: 10.1158/2326-6066.CIR-13-0086. Cancer Immunol Res. 2013. PMID: 24416730 Free PMC article.

2

Modulation of CTLA-4 and GITR for cancer immunotherapy.

Avogadri F, Yuan J, Yang A, Schaer D, Wolchok JD. Avogadri F, et al. Curr Top Microbiol Immunol. 2011;344:211-44. doi: 10.1007/82_2010_49. Curr Top Microbiol Immunol. 2011. PMID: 20563707 Free PMC article. Review.

3

Rational design of anti-GITR-based combination immunotherapy.

Zappasodi R, Sirard C, Li Y, Budhu S, Abu-Akeel M, Liu C, Yang X, Zhong H, Newman W, Qi J, Wong P, Schaer D, Koon H, Velcheti V, Hellmann MD, Postow MA, Callahan MK, Wolchok JD, Merghoub T. Zappasodi R, et al. Nat Med. 2019 May;25(5):759-766. doi: 10.1038/s41591-019-0420-8. Epub 2019 Apr 29. Nat Med. 2019. PMID: 31036879 Free PMC article. Clinical Trial.

4

Agonist anti-GITR monoclonal antibody induces melanoma tumor immunity in mice by altering regulatory T cell stability and intra-tumor accumulation.

Cohen AD, Schaer DA, Liu C, Li Y, Hirschhorn-Cymmerman D, Kim SC, Diab A, Rizzuto G, Duan F, Perales MA, Merghoub T, Houghton AN, Wolchok JD. Cohen AD, et al. Among authors: schaer da. PLoS One. 2010 May 3;5(5):e10436. doi: 10.1371/journal.pone.0010436. PLoS One. 2010. PMID: 20454651 Free PMC article.

5

Anti-GITR antibodies--potential clinical applications for tumor immunotherapy.

Schaer DA, Cohen AD, Wolchok JD. Schaer DA, et al. Curr Opin Investig Drugs. 2010 Dec;11(12):1378-86. Curr Opin Investig Drugs. 2010. PMID: 21154120 Review.

6

Detection of intra-tumor self antigen recognition during melanoma tumor progression in mice using advanced multimode confocal/two photon microscope.

Schaer DA, Li Y, Merghoub T, Rizzuto GA, Shemesh A, Cohen AD, Li Y, Avogadri F, Toledo-Crow R, Houghton AN, Wolchok JD. Schaer DA, et al. PLoS One. 2011;6(6):e21214. doi: 10.1371/journal.pone.0021214. Epub 2011 Jun 22. PLoS One. 2011. PMID: 21731676 Free PMC article.

7

Modulation of GITR for cancer immunotherapy.

Schaer DA, Murphy JT, Wolchok JD. Schaer DA, et al. Curr Opin Immunol. 2012 Apr;24(2):217-24. doi: 10.1016/j.coi.2011.12.011. Epub 2012 Jan 12. Curr Opin Immunol. 2012. PMID: 22245556 Free PMC article. Review.

8

Blockade of surface-bound TGF-β on regulatory T cells abrogates suppression of effector T cell function in the tumor microenvironment.

Budhu S, Schaer DA, Li Y, Toledo-Crow R, Panageas K, Yang X, Zhong H, Houghton AN, Silverstein SC, Merghoub T, Wolchok JD. Budhu S, et al. Among authors: schaer da. Sci Signal. 2017 Aug 29;10(494):eaak9702. doi: 10.1126/scisignal.aak9702. Sci Signal. 2017. PMID: 28851824 Free PMC article.

9

Hiding the road signs that lead to tumor immunity.

Schaer DA, Lesokhin AM, Wolchok JD. Schaer DA, et al. J Exp Med. 2011 Sep 26;208(10):1937-40. doi: 10.1084/jem.20111856. J Exp Med. 2011. PMID: 21948803 Free PMC article. Review.

10

Targeting tumor-necrosis factor receptor pathways for tumor immunotherapy.

Schaer DA, Hirschhorn-Cymerman D, Wolchok JD. Schaer DA, et al. J Immunother Cancer. 2014 Apr 15;2:7. doi: 10.1186/2051-1426-2-7. eCollection 2014. J Immunother Cancer. 2014. PMID: 24855562 Free PMC article. Review.

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