Atadja P - Search Results

1

Differentiation therapy for the treatment of t(8;21) acute myeloid leukemia using histone deacetylase inhibitors.

Bots M, Verbrugge I, Martin BP, Salmon JM, Ghisi M, Baker A, Stanley K, Shortt J, Ossenkoppele GJ, Zuber J, Rappaport AR, Atadja P, Lowe SW, Johnstone RW. Bots M, et al. Among authors: atadja p. Blood. 2014 Feb 27;123(9):1341-52. doi: 10.1182/blood-2013-03-488114. Epub 2014 Jan 10. Blood. 2014. PMID: 24415537 Free PMC article.

2

The histone deacetylase inhibitors LAQ824 and LBH589 do not require death receptor signaling or a functional apoptosome to mediate tumor cell death or therapeutic efficacy.

Ellis L, Bots M, Lindemann RK, Bolden JE, Newbold A, Cluse LA, Scott CL, Strasser A, Atadja P, Lowe SW, Johnstone RW. Ellis L, et al. Among authors: atadja p. Blood. 2009 Jul 9;114(2):380-93. doi: 10.1182/blood-2008-10-182758. Epub 2009 Apr 21. Blood. 2009. PMID: 19383971 Free PMC article.

3

Preclinical screening of histone deacetylase inhibitors combined with ABT-737, rhTRAIL/MD5-1 or 5-azacytidine using syngeneic Vk*MYC multiple myeloma.

Matthews GM, Lefebure M, Doyle MA, Shortt J, Ellul J, Chesi M, Banks KM, Vidacs E, Faulkner D, Atadja P, Bergsagel PL, Johnstone RW. Matthews GM, et al. Among authors: atadja p. Cell Death Dis. 2013 Sep 12;4(9):e798. doi: 10.1038/cddis.2013.306. Cell Death Dis. 2013. PMID: 24030150 Free PMC article.

4

Epigenetics in cancer: targeting chromatin modifications.

Ellis L, Atadja PW, Johnstone RW. Ellis L, et al. Mol Cancer Ther. 2009 Jun;8(6):1409-20. doi: 10.1158/1535-7163.MCT-08-0860. Epub 2009 Jun 9. Mol Cancer Ther. 2009. PMID: 19509247 Review.

5

Histone deacetylase inhibitor panobinostat induces clinical responses with associated alterations in gene expression profiles in cutaneous T-cell lymphoma.

Ellis L, Pan Y, Smyth GK, George DJ, McCormack C, Williams-Truax R, Mita M, Beck J, Burris H, Ryan G, Atadja P, Butterfoss D, Dugan M, Culver K, Johnstone RW, Prince HM. Ellis L, et al. Among authors: atadja p. Clin Cancer Res. 2008 Jul 15;14(14):4500-10. doi: 10.1158/1078-0432.CCR-07-4262. Clin Cancer Res. 2008. PMID: 18628465 Clinical Trial.

6

Antitumor activities and on-target toxicities mediated by a TRAIL receptor agonist following cotreatment with panobinostat.

Martin BP, Frew AJ, Bots M, Fox S, Long F, Takeda K, Yagita H, Atadja P, Smyth MJ, Johnstone RW. Martin BP, et al. Among authors: atadja p. Int J Cancer. 2011 Jun 1;128(11):2735-47. doi: 10.1002/ijc.25594. Epub 2010 Oct 13. Int J Cancer. 2011. PMID: 20715169

7

Combining the differentiating effect of panobinostat with the apoptotic effect of arsenic trioxide leads to significant survival benefit in a model of t(8;21) acute myeloid leukemia.

Salmon JM, Bots M, Vidacs E, Stanley KL, Atadja P, Zuber J, Johnstone RW. Salmon JM, et al. Among authors: atadja p. Clin Epigenetics. 2015 Jan 22;7(1):2. doi: 10.1186/s13148-014-0034-4. eCollection 2015. Clin Epigenetics. 2015. PMID: 25628765 Free PMC article.

8

Correction to: Combining the differentiating effect of panobinostat with the apoptotic effect of arsenic trioxide leads to significant survival benefit in a model of t(8;21) acute myeloid leukemia.

Salmon JM, Bots M, Vidacs E, Stanley KL, Atadja P, Zuber J, Johnstone RW. Salmon JM, et al. Among authors: atadja p. Clin Epigenetics. 2020 Nov 18;12(1):178. doi: 10.1186/s13148-020-00964-9. Clin Epigenetics. 2020. PMID: 33208184 Free PMC article.

9

HDAC Inhibitor Panobinostat Engages Host Innate Immune Defenses to Promote the Tumoricidal Effects of Trastuzumab in HER2⁺ Tumors.

Medon M, Vidacs E, Vervoort SJ, Li J, Jenkins MR, Ramsbottom KM, Trapani JA, Smyth MJ, Darcy PK, Atadja PW, Henderson MA, Johnstone RW, Haynes NM. Medon M, et al. Cancer Res. 2017 May 15;77(10):2594-2606. doi: 10.1158/0008-5472.CAN-16-2247. Epub 2017 Mar 1. Cancer Res. 2017. PMID: 28249907

10

Molecular and biologic characterization and drug sensitivity of pan-histone deacetylase inhibitor-resistant acute myeloid leukemia cells.

Fiskus W, Rao R, Fernandez P, Herger B, Yang Y, Chen J, Kolhe R, Mandawat A, Wang Y, Joshi R, Eaton K, Lee P, Atadja P, Peiper S, Bhalla K. Fiskus W, et al. Among authors: atadja p. Blood. 2008 Oct 1;112(7):2896-905. doi: 10.1182/blood-2007-10-116319. Epub 2008 Jul 25. Blood. 2008. PMID: 18660379 Free article.

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