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208 results

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A better understanding of why murine models of trauma do not recapitulate the human syndrome.
Gentile LF, Nacionales DC, Lopez MC, Vanzant E, Cuenca A, Cuenca AG, Ungaro R, Baslanti TO, McKinley BA, Bihorac A, Cuschieri J, Maier RV, Moore FA, Leeuwenburgh C, Baker HV, Moldawer LL, Efron PA. Gentile LF, et al. Among authors: cuschieri j. Crit Care Med. 2014 Jun;42(6):1406-13. doi: 10.1097/CCM.0000000000000222. Crit Care Med. 2014. PMID: 24413577 Free PMC article.
Differences in outcome between obese and nonobese patients following severe blunt trauma are not consistent with an early inflammatory genomic response.
Winfield RD, Delano MJ, Dixon DJ, Schierding WS, Cendan JC, Lottenberg L, Lopez MC, Baker HV, Cobb JP, Moldawer LL, Maier RV, Cuschieri J. Winfield RD, et al. Among authors: cuschieri j. Crit Care Med. 2010 Jan;38(1):51-8. doi: 10.1097/CCM.0b013e3181b08089. Crit Care Med. 2010. PMID: 19661803 Free PMC article.
Development of a genomic metric that can be rapidly used to predict clinical outcome in severely injured trauma patients.
Cuenca AG, Gentile LF, Lopez MC, Ungaro R, Liu H, Xiao W, Seok J, Mindrinos MN, Ang D, Baslanti TO, Bihorac A, Efron PA, Cuschieri J, Warren HS, Tompkins RG, Maier RV, Baker HV, Moldawer LL; Inflammation and Host Response to Injury Collaborative Research Program. Cuenca AG, et al. Among authors: cuschieri j. Crit Care Med. 2013 May;41(5):1175-85. doi: 10.1097/CCM.0b013e318277131c. Crit Care Med. 2013. PMID: 23388514 Free PMC article.
Advanced age is associated with worsened outcomes and a unique genomic response in severely injured patients with hemorrhagic shock.
Vanzant EL, Hilton RE, Lopez CM, Zhang J, Ungaro RF, Gentile LF, Szpila BE, Maier RV, Cuschieri J, Bihorac A, Leeuwenburgh C, Moore FA, Baker HV, Moldawer LL, Brakenridge SC, Efron PA; Inflammation and Host Response to Injury Investigators. Vanzant EL, et al. Among authors: cuschieri j. Crit Care. 2015 Mar 4;19(1):77. doi: 10.1186/s13054-015-0788-x. Crit Care. 2015. PMID: 25880307 Free PMC article.
Sex-based differences in the genomic response, innate immunity, organ dysfunction, and clinical outcomes after severe blunt traumatic injury and hemorrhagic shock.
Lopez MC, Efron PA, Ozrazgat-Baslanti T, Zhang J, Cuschieri J, Maier RV, Minei JP, Baker HV, Moore FA, Moldawer LL, Brakenridge SC. Lopez MC, et al. Among authors: cuschieri j. J Trauma Acute Care Surg. 2016 Sep;81(3):478-85. doi: 10.1097/TA.0000000000001113. J Trauma Acute Care Surg. 2016. PMID: 27306446 Free PMC article.
The Epidemiology of Chronic Critical Illness After Severe Traumatic Injury at Two Level-One Trauma Centers.
Mira JC, Cuschieri J, Ozrazgat-Baslanti T, Wang Z, Ghita GL, Loftus TJ, Stortz JA, Raymond SL, Lanz JD, Hennessy LV, Brumback B, Efron PA, Baker HV, Moore FA, Maier RV, Moldawer LL, Brakenridge SC. Mira JC, et al. Among authors: cuschieri j. Crit Care Med. 2017 Dec;45(12):1989-1996. doi: 10.1097/CCM.0000000000002697. Crit Care Med. 2017. PMID: 28837430 Free PMC article.
Mitogen-activated protein kinase (MAPK).
Cuschieri J, Maier RV. Cuschieri J, et al. Crit Care Med. 2005 Dec;33(12 Suppl):S417-9. doi: 10.1097/01.ccm.0000191714.39495.a6. Crit Care Med. 2005. PMID: 16340409 Review. No abstract available.
208 results