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180,802 results

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Page 1
High altitude adaptation in Daghestani populations from the Caucasus.
Pagani L, Ayub Q, MacArthur DG, Xue Y, Baillie JK, Chen Y, Kozarewa I, Turner DJ, Tofanelli S, Bulayeva K, Kidd K, Paoli G, Tyler-Smith C. Pagani L, et al. Among authors: chen y. Hum Genet. 2012 Mar;131(3):423-33. doi: 10.1007/s00439-011-1084-8. Epub 2011 Sep 9. Hum Genet. 2012. PMID: 21904933 Free PMC article.
Deleterious- and disease-allele prevalence in healthy individuals: insights from current predictions, mutation databases, and population-scale resequencing.
Xue Y, Chen Y, Ayub Q, Huang N, Ball EV, Mort M, Phillips AD, Shaw K, Stenson PD, Cooper DN, Tyler-Smith C; 1000 Genomes Project Consortium. Xue Y, et al. Among authors: chen y. Am J Hum Genet. 2012 Dec 7;91(6):1022-32. doi: 10.1016/j.ajhg.2012.10.015. Am J Hum Genet. 2012. PMID: 23217326 Free PMC article.
FOXP2 targets show evidence of positive selection in European populations.
Ayub Q, Yngvadottir B, Chen Y, Xue Y, Hu M, Vernes SC, Fisher SE, Tyler-Smith C. Ayub Q, et al. Among authors: chen y. Am J Hum Genet. 2013 May 2;92(5):696-706. doi: 10.1016/j.ajhg.2013.03.019. Epub 2013 Apr 18. Am J Hum Genet. 2013. PMID: 23602712 Free PMC article.
A calibrated human Y-chromosomal phylogeny based on resequencing.
Wei W, Ayub Q, Chen Y, McCarthy S, Hou Y, Carbone I, Xue Y, Tyler-Smith C. Wei W, et al. Among authors: chen y. Genome Res. 2013 Feb;23(2):388-95. doi: 10.1101/gr.143198.112. Epub 2012 Oct 4. Genome Res. 2013. PMID: 23038768 Free PMC article.
A rare functional cardioprotective APOC3 variant has risen in frequency in distinct population isolates.
Tachmazidou I, Dedoussis G, Southam L, Farmaki AE, Ritchie GR, Xifara DK, Matchan A, Hatzikotoulas K, Rayner NW, Chen Y, Pollin TI, O'Connell JR, Yerges-Armstrong LM, Kiagiadaki C, Panoutsopoulou K, Schwartzentruber J, Moutsianas L; UK10K consortium; Tsafantakis E, Tyler-Smith C, McVean G, Xue Y, Zeggini E. Tachmazidou I, et al. Among authors: chen y. Nat Commun. 2013;4:2872. doi: 10.1038/ncomms3872. Nat Commun. 2013. PMID: 24343240 Free PMC article.
Genetic characterization of Greek population isolates reveals strong genetic drift at missense and trait-associated variants.
Panoutsopoulou K, Hatzikotoulas K, Xifara DK, Colonna V, Farmaki AE, Ritchie GR, Southam L, Gilly A, Tachmazidou I, Fatumo S, Matchan A, Rayner NW, Ntalla I, Mezzavilla M, Chen Y, Kiagiadaki C, Zengini E, Mamakou V, Athanasiadis A, Giannakopoulou M, Kariakli VE, Nsubuga RN, Karabarinde A, Sandhu M, McVean G, Tyler-Smith C, Tsafantakis E, Karaleftheri M, Xue Y, Dedoussis G, Zeggini E. Panoutsopoulou K, et al. Among authors: chen y. Nat Commun. 2014 Nov 6;5:5345. doi: 10.1038/ncomms6345. Nat Commun. 2014. PMID: 25373335 Free PMC article.
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