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Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase.
Ping XL, Sun BF, Wang L, Xiao W, Yang X, Wang WJ, Adhikari S, Shi Y, Lv Y, Chen YS, Zhao X, Li A, Yang Y, Dahal U, Lou XM, Liu X, Huang J, Yuan WP, Zhu XF, Cheng T, Zhao YL, Wang X, Rendtlew Danielsen JM, Liu F, Yang YG. Ping XL, et al. Among authors: xiao w. Cell Res. 2014 Feb;24(2):177-89. doi: 10.1038/cr.2014.3. Epub 2014 Jan 10. Cell Res. 2014. PMID: 24407421 Free PMC article.
FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis.
Zhao X, Yang Y, Sun BF, Shi Y, Yang X, Xiao W, Hao YJ, Ping XL, Chen YS, Wang WJ, Jin KX, Wang X, Huang CM, Fu Y, Ge XM, Song SH, Jeong HS, Yanagisawa H, Niu Y, Jia GF, Wu W, Tong WM, Okamoto A, He C, Rendtlew Danielsen JM, Wang XJ, Yang YG. Zhao X, et al. Among authors: xiao w. Cell Res. 2014 Dec;24(12):1403-19. doi: 10.1038/cr.2014.151. Epub 2014 Nov 21. Cell Res. 2014. PMID: 25412662 Free PMC article.
Nuclear m(6)A Reader YTHDC1 Regulates mRNA Splicing.
Xiao W, Adhikari S, Dahal U, Chen YS, Hao YJ, Sun BF, Sun HY, Li A, Ping XL, Lai WY, Wang X, Ma HL, Huang CM, Yang Y, Huang N, Jiang GB, Wang HL, Zhou Q, Wang XJ, Zhao YL, Yang YG. Xiao W, et al. Mol Cell. 2016 Feb 18;61(4):507-519. doi: 10.1016/j.molcel.2016.01.012. Epub 2016 Feb 11. Mol Cell. 2016. PMID: 26876937 Free article.
m(6)A: Signaling for mRNA splicing.
Adhikari S, Xiao W, Zhao YL, Yang YG. Adhikari S, et al. Among authors: xiao w. RNA Biol. 2016 Sep;13(9):756-9. doi: 10.1080/15476286.2016.1201628. Epub 2016 Jun 28. RNA Biol. 2016. PMID: 27351695 Free PMC article. Review.
Cytoplasmic m6A reader YTHDF3 promotes mRNA translation.
Li A, Chen YS, Ping XL, Yang X, Xiao W, Yang Y, Sun HY, Zhu Q, Baidya P, Wang X, Bhattarai DP, Zhao YL, Sun BF, Yang YG. Li A, et al. Among authors: xiao w. Cell Res. 2017 Mar;27(3):444-447. doi: 10.1038/cr.2017.10. Epub 2017 Jan 20. Cell Res. 2017. PMID: 28106076 Free PMC article. No abstract available.
5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m5C reader.
Yang X, Yang Y, Sun BF, Chen YS, Xu JW, Lai WY, Li A, Wang X, Bhattarai DP, Xiao W, Sun HY, Zhu Q, Ma HL, Adhikari S, Sun M, Hao YJ, Zhang B, Huang CM, Huang N, Jiang GB, Zhao YL, Wang HL, Sun YP, Yang YG. Yang X, et al. Among authors: xiao w. Cell Res. 2017 May;27(5):606-625. doi: 10.1038/cr.2017.55. Epub 2017 Apr 18. Cell Res. 2017. PMID: 28418038 Free PMC article.
m6A modulates haematopoietic stem and progenitor cell specification.
Zhang C, Chen Y, Sun B, Wang L, Yang Y, Ma D, Lv J, Heng J, Ding Y, Xue Y, Lu X, Xiao W, Yang YG, Liu F. Zhang C, et al. Among authors: xiao w. Nature. 2017 Sep 14;549(7671):273-276. doi: 10.1038/nature23883. Epub 2017 Sep 6. Nature. 2017. PMID: 28869969
Identification of entacapone as a chemical inhibitor of FTO mediating metabolic regulation through FOXO1.
Peng S, Xiao W, Ju D, Sun B, Hou N, Liu Q, Wang Y, Zhao H, Gao C, Zhang S, Cao R, Li P, Huang H, Ma Y, Wang Y, Lai W, Ma Z, Zhang W, Huang S, Wang H, Zhang Z, Zhao L, Cai T, Zhao YL, Wang F, Nie Y, Zhi G, Yang YG, Zhang EE, Huang N. Peng S, et al. Among authors: xiao w. Sci Transl Med. 2019 Apr 17;11(488):eaau7116. doi: 10.1126/scitranslmed.aau7116. Sci Transl Med. 2019. PMID: 30996080
7,514 results