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Page 1
Mitochondrial respiratory complex III sustains IL-10 production in activated macrophages and promotes tumor-mediated immune evasion.
Zotta A, Toller-Kawahisa J, Palsson-McDermott EM, O'Carroll SM, Henry ÓC, Day EA, McGettrick AF, Ward RW, Ryan DG, Watson MA, Brand MD, Runtsch MC, Maitz K, Lueger A, Kargl J, Miljkovic JL, Lavelle EC, O'Neill LAJ. Zotta A, et al. Among authors: ryan dg. Sci Adv. 2025 Jan 24;11(4):eadq7307. doi: 10.1126/sciadv.adq7307. Epub 2025 Jan 22. Sci Adv. 2025. PMID: 39841829 Free article.
High-dimensional single-cell analysis of human natural killer cell heterogeneity.
Rebuffet L, Melsen JE, Escalière B, Basurto-Lozada D, Bhandoola A, Björkström NK, Bryceson YT, Castriconi R, Cichocki F, Colonna M, Davis DM, Diefenbach A, Ding Y, Haniffa M, Horowitz A, Lanier LL, Malmberg KJ, Miller JS, Moretta L, Narni-Mancinelli E, O'Neill LAJ, Romagnani C, Ryan DG, Sivori S, Sun D, Vagne C, Vivier E. Rebuffet L, et al. Among authors: ryan dg. Nat Immunol. 2024 Aug;25(8):1474-1488. doi: 10.1038/s41590-024-01883-0. Epub 2024 Jul 2. Nat Immunol. 2024. PMID: 38956378 Free PMC article.
Multifaceted mitochondria in innate immunity.
Marques E, Kramer R, Ryan DG. Marques E, et al. Among authors: ryan dg. NPJ Metab Health Dis. 2024;2(1):6. doi: 10.1038/s44324-024-00008-3. Epub 2024 May 27. NPJ Metab Health Dis. 2024. PMID: 38812744 Free PMC article. Review.
Immunometabolism at the basis of health and disease; an editorial.
Van den Bossche J, Horng T, Ryan DG. Van den Bossche J, et al. Among authors: ryan dg. Biochim Biophys Acta Mol Basis Dis. 2023 Aug;1869(6):166715. doi: 10.1016/j.bbadis.2023.166715. Epub 2023 Apr 6. Biochim Biophys Acta Mol Basis Dis. 2023. PMID: 37030523 Free article. No abstract available.
Macrophage fumarate hydratase restrains mtRNA-mediated interferon production.
Hooftman A, Peace CG, Ryan DG, Day EA, Yang M, McGettrick AF, Yin M, Montano EN, Huo L, Toller-Kawahisa JE, Zecchini V, Ryan TAJ, Bolado-Carrancio A, Casey AM, Prag HA, Costa ASH, De Los Santos G, Ishimori M, Wallace DJ, Venuturupalli S, Nikitopoulou E, Frizzell N, Johansson C, Von Kriegsheim A, Murphy MP, Jefferies C, Frezza C, O'Neill LAJ. Hooftman A, et al. Among authors: ryan dg. Nature. 2023 Mar;615(7952):490-498. doi: 10.1038/s41586-023-05720-6. Epub 2023 Mar 8. Nature. 2023. PMID: 36890227 Free PMC article.
Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression.
Sciacovelli M, Dugourd A, Jimenez LV, Yang M, Nikitopoulou E, Costa ASH, Tronci L, Caraffini V, Rodrigues P, Schmidt C, Ryan DG, Young T, Zecchini VR, Rossi SH, Massie C, Lohoff C, Masid M, Hatzimanikatis V, Kuppe C, Von Kriegsheim A, Kramann R, Gnanapragasam V, Warren AY, Stewart GD, Erez A, Vanharanta S, Saez-Rodriguez J, Frezza C. Sciacovelli M, et al. Among authors: ryan dg. Nat Commun. 2022 Dec 20;13(1):7830. doi: 10.1038/s41467-022-35036-4. Nat Commun. 2022. PMID: 36539415 Free PMC article.
Metabolic symbiosis in pancreatic cancer.
Ryan DG, Frezza C. Ryan DG, et al. Nat Cancer. 2022 Nov;3(11):1277-1278. doi: 10.1038/s43018-022-00454-2. Nat Cancer. 2022. PMID: 36411319 No abstract available.
Macrophage innate training induced by IL-4 and IL-13 activation enhances OXPHOS driven anti-mycobacterial responses.
Lundahl MLE, Mitermite M, Ryan DG, Case S, Williams NC, Yang M, Lynch RI, Lagan E, Lebre FM, Gorman AL, Stojkovic B, Bracken AP, Frezza C, Sheedy FJ, Scanlan EM, O'Neill LAJ, Gordon SV, Lavelle EC. Lundahl MLE, et al. Among authors: ryan dg. Elife. 2022 Sep 29;11:e74690. doi: 10.7554/eLife.74690. Elife. 2022. PMID: 36173104 Free PMC article.
36 results